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Multistep Syntheses

  • Francis A. Carey
  • Richard J. Sundberg
Part of the Advanced Organic Chemistry book series

Abstract

The preceding chapters have discussed many of the reactions which are important tools for organic synthesis. Although some of the problems which accompany these chapters have dealt with synthesis, little has been said explicitly about the subject of multistep synthesis. In this chapter, the focus will be on multistep synthesis, using as essential background the knowledge of chemical reactions developed in the preceding chapters. The kinds of synthetic problems that are a challenge to organic synthetic techniques at present generally involve multifunctional molecules. Multistep synthesis therefore requires planning for the compatibility of proposed reactions with the various functional groups in the molecule. In Section 11.1, Protective Groups, we will consider ways of temporarily modifying functional groups that would otherwise interfere with reactions at other points in the molecule. In Section 11.2, Synthetic Equivalent Groups, the use of reactions which introduce or transform a functionality while in a “masked” form will be considered.

Keywords

Enantiomeric Excess Chiral Center Protective Group Asymmetric Synthesis Enantioselective Synthesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • Francis A. Carey
    • 1
  • Richard J. Sundberg
    • 1
  1. 1.University of VirginiaCharlottesvilleUSA

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