Pathophysiology of the Aging Heart and Circulation

  • Jerome L. Fleg
  • Gary Gerstenblith
  • Edward G. Lakatta
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 31)


Although both the prevalence and incidence of cardiovascular disease increase dramatically with advancing age, aging and disease are not synonymous. Therefore, when studying the aging process in man, one must omit those changes in the elderly groups that, in reality, are due to the presence or development of disease This chapter will attempt to delineate those changes in the heart and peripheral vasculature at rest and during exercise that are thought to represent “normal” aging. While these changes in and of themselves, usually cause no disability, they do provide an altered substrate on which the specific cardiovascular diseases to be discussed in subsequent chapters are superimposed. The signs, symptoms, and clinical course of these pathologic processes may be modified significantly by the physiological aging of the cardiovascular system.


Stroke Volume Constrictive Pericarditis Systolic Time Interval Aging Heart Peripheral Vasculature 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media Dordrecht 1984

Authors and Affiliations

  • Jerome L. Fleg
  • Gary Gerstenblith
  • Edward G. Lakatta

There are no affiliations available

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