Advertisement

Metastatic Carcinoma in the Ovary

  • Ancel Blaustein

Abstract

The ovary is a fairly frequent site of metastasis from certain primary carcinomas; approximately 10% of ovarian tumors are not primary in origin.6,910,19,22 The most common metastasis is from a carcinoma arising in the endometrium. Other primary tumors that have a predeliction for metastasis to the ovary are from the gastrointestinal (GI) tract2 and breast.5,11 Tumors that metastasize to the ovary much less frequently include those arising in the cervix, fallopian tube, pancreas, gallbladder, lung, and cutaneous melanoma. A study of secondary ovarian carcinoma by Woodruff and Novak22 demonstrated that at least 50% of the primary tumors giving rise to ovarian metastases were below the diaphragm and 13% above. Metastatic carcinoma to the ovary is bilateral in from 70 to 90% of cases7,9,22; unilateral involvement usually is found where metastasis occurs by contiguity. There are, however, instances of unilateral metastases that are difficult to explain, e.g., from the breast or the GI tract.

Keywords

Obstet Gynecol Carcinoid Tumor Endometrial Carcinoma Metastatic Carcinoma Granulosa Cell Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Bullon A Jr, Arseneau J, Prat J, Young RH, Scully RE (1981) Tubular Krukenberg Tumors: A problem in histopathological diagnosis. Am J Surg Pathol (in press)Google Scholar
  2. 2.
    Burt CAV (1957) Prophylactic oophorectomy with resection of the large bowel for cancer. Am J Surg 93: 77PubMedCrossRefGoogle Scholar
  3. 3.
    Esau D (1933) Krukenberg tumoren in der Schwangerschaft. Nachtrag zu der arbeit von Dr. Puppel. Zentvalbl f Gynak 57: 1167Google Scholar
  4. 4.
    Finn WF (1951) Diagnostic confusion of ovarian metastases from endometrial carcinoma with primary ovarian carcinoma. Am J Obstet Gynecol 62: 403PubMedGoogle Scholar
  5. 5.
    Haagerson CD (1971) Diseases of the Breast, 2nd ed. Philadelphia, W. B. SaundersGoogle Scholar
  6. 6.
    Haines M (1971) Carcinoid tumors of the ovary. J Obstet Gynaecol Br Commonw 78: 1123PubMedCrossRefGoogle Scholar
  7. 7.
    Hall-Allan RTJ (1969) Metastatic ovarian carcinoid tumor. Postgrad Med J 45: 46CrossRefGoogle Scholar
  8. 8.
    Hopping RA, Dockerty MB, Masson JC (1942) Carcinoid tumors of the appendix—report of a case in which extensive intraabdominal metastases occurred, including involvement of the right ovary. Arch Surg 45: 613CrossRefGoogle Scholar
  9. 9.
    Israel SS, Helsel EV Jr, Hausman DH (1965) The challenge of metastatic ovarian carcinoma. Am J Obstet Gynecol 93: 1094PubMedGoogle Scholar
  10. 10.
    Karsh J (1951) Secondary malignant disease of the ovary. Am J Obstet Gynecol 61: 154PubMedGoogle Scholar
  11. 11.
    Kasilag FB Jr, Ruthledge FN (1957) Metastatic breast carcinoma of the ovary. Am J Obstet Gynecol 74: 989PubMedGoogle Scholar
  12. 12.
    Krukenberg P (1896) Ueben das Fibrosarcoma Ovarii Mucocellulari (carcinomatoses). Arch Gyn Munch 50: 287CrossRefGoogle Scholar
  13. 13.
    Lee YN, Hori JM (1971) Significance of ovarian metastasis in therapeutic oophorectomy for advanced breast cancer. Cancer 27: 1374PubMedCrossRefGoogle Scholar
  14. 14.
    Martzloff KH, Manlove CH (1949) Vaginal and ovarian metastases from hypernephroma: Report of a case and review of literature. Surg Gynecol Obstet 88: 145PubMedGoogle Scholar
  15. 15.
    Munnell EW, Taylor HC, Jr (1949) Ovarian carcinoma: Review of 200 primary and 51 secondary cases. Am J Obstet Gynecol 58: 943PubMedGoogle Scholar
  16. 16.
    Ober WB, Pollak A, Gerstmann KE, Kupperman HS (1962) Krukenberg tumor with androgenic and progestational activity. Am J Obstet Gynecol 84: 739PubMedGoogle Scholar
  17. 17.
    Robboy SJ, Scully RE, Norris HT (1974) Carcinoid—metastatic to the ovary. Cancer 33: 798PubMedCrossRefGoogle Scholar
  18. 18.
    Schlagenhaufer F (1902) Uber das Metastatische Ovarialkarzinom Nach Krebs das Magens, Darmes und anderer Bachorgane. Mschv Geburtsh Gyak 15: 485Google Scholar
  19. 19.
    Scully RE (1970) Recent progress of ovarian cancer. Hum Pathol 1: 73PubMedCrossRefGoogle Scholar
  20. 20.
    Shuster M, Mendoza-Divino E, Joelson H (1970) H Carcinoid tumor metastasizing to the ovaries. Obstet Gynecol 36: 515PubMedGoogle Scholar
  21. 21.
    Turenen K (1955) Hormonal secretion of Krukenberg tumors. Acta Endocrinol 20: 50Google Scholar
  22. 22.
    Woodruff JD, Novak ER (1960) Krukenberg tumors of the ovary. Obstet Gynecol 15: 351PubMedGoogle Scholar
  23. 23.
    Woodruff JD, Williams JJ, Goldberg B (1963) Hormone activity of the common ovarian neoplasms. Am J Obstet Gynecol 87: 679PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1982

Authors and Affiliations

  • Ancel Blaustein

There are no affiliations available

Personalised recommendations