The Laws of Probability and Their Application to Prokaryote Cultures
The preceding chapter included discussions of some of the problems associated with the analysis of prokaryotic genetic systems. An additional theoretical problem which must be considered is that of sampling. As noted earlier, it is not generally possible to recover all of the progeny from a cross, due to the necessity of using some sort of selective technique to find a few recombinant individuals among many parental types. Therefore, in designing prokaryotic genetic experiments, it is essential to be certain both that the sample is representative of the entire population of organisms and that the sample is of a suitable size to compensate for the random variation which is observed in any physical procedure. The former concern can be alleviated by good culture agitation techniques which provide a homogeneous population from which to sample. The latter concern is the subject of this chapter.
KeywordsInfected Cell Mutant Cell Phage Particle Prob Ability Poisson Approximation
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