Coccidioidal infection of the eye is thought to be a rare complication of disseminated disease. It is, however, of historical interest that ocular involvement was described by Rixford and Gilchrist in their first patient.1 Furthermore, eye findings have been reported as the only manifestation of dissemination in some patients.2,3 Since previous reviews,4–6 additional case reports have been published and are included in this report. Also discussed is new information concerning potentially beneficial antifungal agents that have become available.
KeywordsAnterior Uveitis Ocular Involvement Ocular Manifestation Additional Case Report Chorioretinal Lesion
Unable to display preview. Download preview PDF.
- 1.E. Rixford and T. C. Gilchrist, Two cases of protozoan (coccidioidal) infection of the skin and other organs, Johns Hopkins Hosp. Rep. 1: 209–268 (1896).Google Scholar
- 4.D. H. Trowbridge, Ocular manifestations of coccidioidomycosis, Trans. Pac. Coast Oto-Ophthalmol. Soc. 33: 229–244 (1952).Google Scholar
- 5.M. J. Fiese, Coccidioidomycosis, Charles C. Thomas, Springfield, Ill. (1958).Google Scholar
- 6.J. Francois and M. Rysselaere, Oculomycoses, Charles C. Thomas, Springfield, Ill. (1972).Google Scholar
- 10.J. W. Wilson and O. A. Plunkett, The Fungus Diseases of Man, University of California Press, Berkeley and Los Angeles (1965).Google Scholar
- 13.R. F. Faulkner, Ocular coccidioidomycosis. Report of a case of coccidioidal granuloma of the conjunctiva associated with cutaneous coccidioidomycosis, Am. J. Ophthalmol. 45: 822–827 (1958).Google Scholar
- 25a.H. T. Rodenbeker, J. P. Ganley, J. N. Galgiani, and S. G. Axline, Prevalence of chorioretinal scars associated with coccidioidomycosis, Arch. Ophthalmol. (in press).Google Scholar
- 26.M. S. Blumenkranz and D. A. Stevens, Endogenous coccidioidal endophthalmitis, Ophthalmology (in press).Google Scholar
- 28.A. J. Hagele, D. J. Evans, and T. R. Larwood, Primary endophthalmic coccidioidomycosis: Report of a case of exogenous primary coccidioidomycosis of the eye diagnosed prior to enucleation, in: Coccidioidomycosis ( L. Ajello, ed.), University of Arizona Press, Tucson (1967), pp. 37–39.Google Scholar
- 32.D. A. Stevens, Miconazole in the treatment of systemic fungal infections, Am. Rev. Resp. Dis. 116: 801–806 (1978).Google Scholar
- 33.L. I. Lutwick, J. N. Galgiani, R. H. Johnson, and D. A. Stevens, Visceral fungal infections due to Petriellidium boydii (Allescheria boydii). In vitro drug sensitivity studies, Am. J. Med. 61:632–640 (1976).Google Scholar
- 34.M. S. Blumenkranz and D. A. Stevens, Therapy of endogenous fungal endophthalmitis: miconazole or amphotericin for coccidioidal and candidal infection, Arch. Ophthalmol. (in press).Google Scholar