Role of DNA Repair in Aging

  • Ronald W. Hart


Aging--which appears to be the most pervasive degenerative process occurring in the higher animals--is of such general occurrence and characterized by such a diversity of clinically and biochemically defined changes that a specific definition, other than a general loss of the capacity of an organism or cell to function at a level previously characterized as normal, is the only definition presently agreed upon by all gerontobiologists. Due to the generalized nature of the aging process, it is reasonable to assume that if any single molecular target for the aging phenomenon does exist, it must be related not only to age-related diseases, but also play a central role in several cellular processes.


Excision Repair Placental Mammal Xeroderma Pigmentosum Pyrimidine Dimer Human Fibroblast Culture 
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Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • Ronald W. Hart
    • 1
  1. 1.Department of RadiologyThe Ohio State University Hospitals (N-212)USA

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