Abstract
The areas of predilection for atherosclerosis and thrombosis in the vascular system are characterized by curvature, branching, bifurcation or embanking. We have investigated induced thrombus formation at arteriolar bifurcations with migrating stagnation points and local vortex flow. Thrombogenic endothelial lesions were produced by argon laser injury or by photochemical reactions (using FITC-dextran 70). The following items have been evaluated: local red blood cell velocity, geometry of the vessel, localization of the first thrombus growth. The first appearance of thrombus formation at presumably reattachment points at bifurcations in the microcirculation could be directly demonstrated by intravital microscopy.
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Seiffge, D., Kremer, E., Laux, V., Reifert, P. (1990). Investigations Concerning Localization of Induced Thrombus Formation at Arteriolar Branchings. In: Mosora, F., Caro, C.G., Krause, E., Schmid-Schönbein, H., Baquey, C., Pelissier, R. (eds) Biomechanical Transport Processes. NATO ASI Series, vol 193. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1511-8_36
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DOI: https://doi.org/10.1007/978-1-4757-1511-8_36
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