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Morphological and Quantitative Aspects of Bone Formation and Mineralization

  • Gastone Marotti
Conference paper
Part of the NATO ASI Series book series (NSSA, volume 184)

Abstract

Bone formation is a biphasic process. During the first phase, the osteoblasts secrete an organic matrix, called preosseous matrix or osteoid, made up of type I collagen and ground substance (proteoglycans, glycoproteins, non-collagenous proteins). During the second phase, mineralization occurs, transforming the osteoid into bone tissue. Analyzed from the morphological viewpoint, three main aspects must be taken into account in osteogenesis of cellular bone: osteoblast dynamics, namely the mechanism by which the osteoblasts modulate the bone appositional growth rate; osteoblast-osteocyte transformation; osteoblast control of collagen orientation.

Keywords

Cytoplasmic Process Collagen Orientation Lamellar Bone Osteocyte Lacuna Osteoid Seam 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • Gastone Marotti
    • 1
  1. 1.Istituto di Anatomia umana normaleUniversità di Modena PoliclinicoModenaItaly

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