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Purine Metabolism in Man pp 799–806Cite as

The Use of High Pressure Liquid Chromatography to Monitor Nucleotide Levels in Cells

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 41))

Abstract

High pressure liquid chromatography has proved to be a valuable tool in measuring the nucleotide levels in cell extracts (1, 2). The analyses are accomplished with high speed, sensitivity, resolution and accuracy. A decided advantage of this technique is that the major naturally occurring nucleotides can be monitored at one time concurrently with nucleotides of purine and pyrimidine analogs.

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Author information

Authors and Affiliations

  1. Division of Biological and Medical Sciences, Brown University, Providence, RI, 02912, USA

    Phyllis R. Brown & R. E. Parks Jr.

Authors
  1. Phyllis R. Brown
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  2. R. E. Parks Jr.
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Editor information

Editors and Affiliations

  1. Division of Metabolic Disease, Rogoff-Wellcome Medical Research Institute, Beilinson Hospital, Petah-Tikva, Israel

    Oded Sperling  & Andre De Vries  & 

  2. Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA

    James B. Wyngaarden

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© 1974 Springer Science+Business Media New York

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Brown, P.R., Parks, R.E. (1974). The Use of High Pressure Liquid Chromatography to Monitor Nucleotide Levels in Cells. In: Sperling, O., De Vries, A., Wyngaarden, J.B. (eds) Purine Metabolism in Man. Advances in Experimental Medicine and Biology, vol 41. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-1433-3_58

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  • DOI: https://doi.org/10.1007/978-1-4757-1433-3_58

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4757-1435-7

  • Online ISBN: 978-1-4757-1433-3

  • eBook Packages: Springer Book Archive

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