Skip to main content
SpringerLink
Log in

Hyperuricemia Induced by Ethambutol

  • Chapter
  • First Online:
Purine Metabolism in Man

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 41))

Abstract

Ethambutol is commonly used to treat infections in man caused by Mycobacterium tuberculosis (Fig. 1). We have found that ethambutol also produces a substantial increase in the serum urate concentration in many patients receiving this agent (Postlethwaite, et al., 1972).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Gutman, A. B. and Yu, T. F. 1957. Protracted uricosuric therapy in tophaceous gout. Lancet 2: 1258–1260.

    Article  Google Scholar 

  • Lieber, C. S., Jones, D. P., Losowsky, M. S. and Davidson, C. S. 1962. Interrelation of uric acid and ethanol metabolism in man. J. Clin. Invest. 41: 1863–1870.

    Article  CAS  Google Scholar 

  • Petty, T. L. and Dalrymple, G. V. 1964. Inhibition of pyrazinamide hyperuricemia by small doses of acetylsalicylic acid. Ann. Intern. Med. 60: 898–900.

    Article  CAS  Google Scholar 

  • Postlethwaite, A. E. and Kelley, W. N. 1972. Radiocontrast agents and aspirin. J.A.M.A. 219: 1479.

    Article  CAS  Google Scholar 

  • Postlethwaite, A. E., Bartel, A. G. and Kelley, W. N. 1972.

    Google Scholar 

  • Hyperuricemia due to ethambutol. New Eng. J. Med. 286: 761-762.

    Google Scholar 

  • Schirmeister, J., Mau, N. K. and Hallaner, W. 1969. Study on renal and extrarenal factors involved in the hyperuricemia induced by furosemide, p. 59. In G. Peters and F. Roch-Ramel (eds.), Progress in Nephrology. Springer-Verlag, Inc., Berlin.

    Google Scholar 

  • Steele, T. H. and Oppenheimer, S. 1969. Factors affecting urate excretion following diuretic administration in man. Amer. J. Med. 47: 564–574.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Medicine, Duke University Medical Center, Durham, North Carolina, 27710, USA

    A. E. Postlethwaite, A. G. Bartel & W. N. Kelley

Authors
  1. A. E. Postlethwaite
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. G. Bartel
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. W. N. Kelley
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Division of Metabolic Disease, Rogoff-Wellcome Medical Research Institute, Beilinson Hospital, Petah-Tikva, Israel

    Oded Sperling  & Andre De Vries  & 

  2. Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA

    James B. Wyngaarden

Rights and permissions

Reprints and permissions

Copyright information

© 1974 Springer Science+Business Media New York

About this chapter

Cite this chapter

Postlethwaite, A.E., Bartel, A.G., Kelley, W.N. (1974). Hyperuricemia Induced by Ethambutol. In: Sperling, O., De Vries, A., Wyngaarden, J.B. (eds) Purine Metabolism in Man. Advances in Experimental Medicine and Biology, vol 41. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-1433-3_52

Download citation

  • DOI: https://doi.org/10.1007/978-1-4757-1433-3_52

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4757-1435-7

  • Online ISBN: 978-1-4757-1433-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation