Reduced Renal Ammoniagenesis in Primary Gout

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 41)


The rate of NH3diffusion is influenced by (1) the transtubular pH gradient, (2) the availability of titratable acid precursors, and (3) the urine flow rates. In our subjects for the present study of urinary excretion of titratable acid, NH+4, and uric acid, urine samples were collected as a rule from 6:30 A. M. to 8:30 A. M. after an overnight fast, both the gouty and the non-gouty subjects alike. the urine flow rates were more or less in the same range, approximately 1.0 ± 0.3 ml/min.


Uric Acid Titratable Acid Urine Flow Rate Acid Loading Urinary Uric Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer Science+Business Media New York 1974

Authors and Affiliations

  1. 1.Mount Sinai School of MedicineCity University of New YorkNew YorkUSA

Personalised recommendations