Ethanol Elimination is Inherited in the Rat

  • Ronald G. Thurman


Ethanol metabolism was shown to be heritable in male and female Sprague-Dawley rats. In addition, the stimulated rate of ethanol elimination following 24 hours of treatment with ethanol was also shown to be heritable. F1 and F2 progeny for the two phenotypes (naive and adapted rates) resembled their selected parents rather than the unselected population.


Selective Breeding Chronic Ethanol Ethanol Treatment Unselected Population Naive Rate 


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Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • Ronald G. Thurman
    • 1
  1. 1.Department of PharmacologyUniversity of North CarolinaChapel HillUSA

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