Protective Activity of Thymosin α1 Against Tumor Progression in Immunosuppressed Mice

  • Hideo Ishitsuka
  • Yukio Umeda
  • Atsuko Sakamoto
  • Yasuo Yagi
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 166)


Thymus gland has been shown to play an important role in the development, growth and function of lymphoid systems through a hormonal mechanism. One of the thymic hormones, thymosin (1), stimulates T cell development and corrects some immunodeficiency diseases resulting from lack of thymus functions. Considering the importance of T cells in immunoregulatory systems, thymosin is expected to be useful as a pharmaceutical agent for a variety of diseases which are caused by or which accompany the aberration of these systems.


Natural Killer Natural Killer Cell Normal Mouse Spleen Cell Pulmonary Metastasis 


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Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • Hideo Ishitsuka
    • 1
  • Yukio Umeda
    • 1
  • Atsuko Sakamoto
    • 1
  • Yasuo Yagi
    • 1
  1. 1.Nippon Roche Research CenterKamakura City, Kanagawa Pref. 247Japan

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