Drugs Acting on Respiratory Muscles
Many drugs may act on the skeletal muscles including the respiratory muscles. Involvement of the respiratory muscles is of interest as it may change the pulmonary functions and ultimately the gas exchange. This review will not consider all the drugs which may affect the skeletal muscles but will focus on several particular points which may be of interest to the respiratory physiologist or the clinician.
KeywordsTidal Volume Respiratory Muscle Breathing Pattern Breathing Frequency Intercostal Muscle
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- 1.Gautier, H. and Gaudy, J. H. (1978) . Changes in ventilatory pattern induced by intravenous anaesthetic agents in human subjects. J. appl. Physiol., 45, 171–176.Google Scholar
- 3.Hedenstierna, G., Lofstrom, B. and Lundh, R. (1981) . Thoracic gas volume and chest-abdomen dimensions during anaesthesia and muscle paralysis. Anesthesiology, 55, 499–506.Google Scholar
- 4.Westbrook, P. R., Stubbs, S. E., Sessler, A. D., Rehder, K. and Hyatt, R. E. (1973). Effects of anaesthesia and muscle paralysis on respiratory mechanics in normal man. J. appl. Physiol., 34, 81–86.Google Scholar
- 11.Gautier, H. and Bonora, M. (1982). Effects of hypoxia and respiratory stimulants in conscious intact and carotid-denervated cats. Bull. europ. Physiopath. Resp., 18, 565–582.Google Scholar
- 13.Gal, T. J., and Arora, N. S. (1982). Respiratory mechanics in supine subjects during progressive partial curarization. J. appl. Physiol., 52, 57–63.Google Scholar
- 14.Campbell, E. J. M., Freedman, S., Clark, T. J. H., Robson, J. G. and Norman, J. (1967). The effect of muscular paralysis induced by tubocurarine on the duration and sensation of breathhold ing. Clin. Sci., 32, 425–432.Google Scholar
- 16.Johansen, S. H., Jorgensen, M., and Molbech, S. (1964). Effect of tubocurarine on respiratory and nonrespiratory muscle power in man. J. appl. Physiol., 19, 990–994.Google Scholar
- 17.Gautier, H. and Vincent, J. (1981). Muscle relaxants and breathing. In: Respiratory Pharmacology, J. G. Widdicombe, Ed., Pergamon Press, Chapter 16, pp. 335–342.Google Scholar