Single amino acid alterations in one of the three ras proteins have been detected in 25–50% of human cancers and it is believed that the somatic mutational event which generated these amino acid substitutions was an important step in the development of these malignancies (Barbacid, 1986; Bos et al., 1987; Paterson et al., 1987).
KeywordsInositol Phosphate Intrinsic GTPase Activity Inositol Phosphate Production Bombesin Receptor Mouse Mammary Tumour Virus Promoter
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