Thrombosis pp 311-321 | Cite as

A Discussion of Methods for Predicting Patients Who are Prone to Platelet Thromboembolism Including Measurements of Blood Components

  • J. C. Hoak
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 102)


The belief that aggregates of platelets may develop in the circulation and interfere with the vascular supply to vital organs is certainly not a new concept. It received further support from the observations of morphologists who found platelet aggregates as prominent components of thrombi and from studies in which the infusion of aggregating agents into local vascular beds caused organ injury or infarction in association with the formation of platelet aggregates. These lesions failed to develop if the animals were treated with inhibitors of platelet aggregation prior to the infusion of the aggregating agent.


Transient Cerebral Ischemia Granulomatous Hepatitis Platelet Survival Recurrent Deep Vein Thrombosis Aggregate Test 
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Copyright information

© Springer Science+Business Media New York 1978

Authors and Affiliations

  • J. C. Hoak
    • 1
  1. 1.Division of Hematology-Oncology, Department of Medicine and the Cardiovascular CenterUniversity of IowaIowa CityUSA

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