Nonvenereal Treponematoses

  • Peter L. Perine


The endemic treponematoses are a group of chronic diseases affecting primarily the skin of children and young adults who live in remote, impoverished areas between the tropics of Cancer and Capricorn. They are considered as a group because they have many clinical, pathologic, and epidemiologic features in common (Table 1). They are also caused by spirochetes that are closely related to one another and to Treponema pallidum of venereal syphilis. (11) These diseases with their etiologic treponeme in order of their worldwide prevalence are: yaws (T. pallidum ssp. pertenue), endemic syphilis (T. pallidum ssp. endemicum), and pinta (T. carateum).( 18 ) Other related treponemes cause venereal syphilis in rabbits (T. cuniculi) and asymptomatic infections in African baboons (T. freiborg-blanc) but they have no epidemiologic significance as far as human infections are concerned.


Initial Lesion Penicillin Treatment Acute Bacterial Infection Congenital Transmission Serous Exudate 


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12. Suggested Reading

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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • Peter L. Perine
    • 1
  1. 1.Division of Tropical Public Health, Department of Preventive Medicine, F. Edward Hébert School of MedicineUniformed Services University of the Health SciencesBethesdaUSA

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