Abstract
During the 1940s and 1950s, a series of outbreaks of diarrhea in hospital newborn nurseries were reported in which the etiological agent appeared to be Escherichia coli identified by serotype. These strains became known as enteropathogenic E. coli (EPEC). Although it is generally recognized that these strains are responsible for diarrhea among children under 2 years of age, only now are we beginning to understand how they produce disease.
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12. Suggested Reading
Dupont, H. L., Formal, S. B., Hornick, R. B., Snyder, M. J., Libonati, J. P., Sheahan, D. G., Labrec, E. H., and Kalas, J. P., Pathogenesis of Escherichia coli diarrhea, N. Engl. J. Med. 285:1–9 (1971).
Dupont, H. L., and Pickering, L. K., Infections of the Gastrointestinal Tract: Microbiology, Pathophysiology, and Clinical Features, Plenum Medical, New York, 1980.
Edelman, R., and Levine, M. M., Summary of a workshop on enteropathogenic Escherichia coli, J. Infect. Dis. 147:1108–1118 (1983).
Levine, M. M., Kaper, J. B., Black, R. E., and Clements, M. L., New knowledge of the pathogenesis of bacterial enteric infections as applied to vaccine development, Microbiol. Rev. 47:510–550 (1983).
Riley, L. W., Remis, R. S., Helgerson, S. D., Mcgee, H. B., Wells, J. G., Davis, B. R., Hebert, R. J., Olcott, E. S., Johnson, L. M., Hargrett, N. T., Blake, P. A., and Cohen, M. L., Hemorrhagic colitis associated with a rare Escherichia coli serotype, N. Engl. J. Med. 308:681–685 (1983).
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DuPont, H.L., Mathewson, J.J. (1991). Escherichia coli Diarrhea. In: Evans, A.S., Brachman, P.S. (eds) Bacterial Infections of Humans. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1211-7_12
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