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Mechanism of Action of Antiarrhythmic Drugs

  • Luc M. Hondeghem
  • Bertram G. Katzung
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 34)

Abstract

In this chapter we describe the modulated receptor hypothesis for the action of certain antiarrhythmic drugs. We briefly review the work that led to this hypothesis, present a detailed description of the mechanism, and apply it to a group of antiarrhythmic agents and the arrhythmias in which they are used.

Keywords

Antiarrhythmic Drug Action Potential Duration Sodium Current Purkinje Fiber Voltage Shift 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media Dordrecht 1984

Authors and Affiliations

  • Luc M. Hondeghem
  • Bertram G. Katzung

There are no affiliations available

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