Introduction: The Practice of Pharmacotherapy
Experimentation with drugs that alter mood, thinking, or perception represents a timeless human enterprise. Although largely aimed at the relief of suffering, the utilization of various pharmacological agents also reflects different cultural, religious, and political ideologies. Frequently, implementing effective pharmacological treatments depends more on social issues, economic considerations, and serendipity than on clinical factors. A historical account of the discovery and introduction of psychoactive drugs in the United States highlights these patterns.
KeywordsTemporal Lobe Epilepsy Psychoactive Drug Drug Trial Lithium Salt Bipolar Affective Disorder
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- 1.Sen G., Bose K. C.: Rauwolfia serpentina, a new Indian drug for insanity and high blood pressure. Indian Med World 2:194–201, 1931.Google Scholar
- 5.Sternback L. H., Randall L. O., Gustafson, S. R.: 1,4-Benzodiazepines: Chlordiazepoxide and related compounds, in Gordon M. (ed): Psychopharmacological Agents. New York, Academic Press, 1964, vol 1, 137–224.Google Scholar
- 7.Group for the Advancement of Psychiatry: Pharmacotherapy and Psychotherapy: Paradoxes, Problems and Progress, report 93. New York, Group for the Advancement of Psychiatry, 1975, vol 9.Google Scholar
- 9.Beck A. T., Rush A. J., Shaw B. F., et al: Cognitive Therapy of Depression. New York, Guilford Press, 1979.Google Scholar
- 10.Gelenberg A. J.: New perceptions on the use of tricyclic antidepressants. J Clin Psychiatry 50:7(Suppl):3–10, 1989.Google Scholar