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The Chemical Hazard of Anti-Implantation Assessed and Analyzed Both In Vitro and In Vivo

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The Use of Human Cells for the Evaluation of Risk from Physical and Chemical Agents

Abstract

I was tempted to offer this paper for several reasons. The term hazard describes the nature of something undesirable which may happen to an individual or population while the term risk describes the probability that the hazard will happen. Plainly identification of the hazard has to precede the assessment of risk. My paper describes a novel in vitro technique for the demonstration of and quantitation of the hazard of oestrogenicity using the maturation and implantation of the developing mouse embyro.

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References

  1. P. V. Holmes and A. D. Dickson, Estrogen-induced surface and enzyme changes in the implantating mouse blastocyst, J. Embryol. Exp. Morphol., 29: 639–645 (1973).

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© 1983 Springer Science+Business Media New York

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Pugh, D.M., Sumano, H.S. (1983). The Chemical Hazard of Anti-Implantation Assessed and Analyzed Both In Vitro and In Vivo . In: Castellani, A. (eds) The Use of Human Cells for the Evaluation of Risk from Physical and Chemical Agents. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1117-2_47

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  • DOI: https://doi.org/10.1007/978-1-4757-1117-2_47

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-1119-6

  • Online ISBN: 978-1-4757-1117-2

  • eBook Packages: Springer Book Archive

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