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The Chemical Hazard of Anti-Implantation Assessed and Analyzed Both In Vitro and In Vivo

  • D. Michael Pugh
  • Hector S. Sumano

Abstract

I was tempted to offer this paper for several reasons. The term hazard describes the nature of something undesirable which may happen to an individual or population while the term risk describes the probability that the hazard will happen. Plainly identification of the hazard has to precede the assessment of risk. My paper describes a novel in vitro technique for the demonstration of and quantitation of the hazard of oestrogenicity using the maturation and implantation of the developing mouse embyro.

Keywords

Chemical Hazard Mouse Blastocyst Post Coitum Tubal Transport Genicity Risk Assessment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    D. M. Pugh and H. S. Sumano, The anti-implantation action of tamoxifen in mice, Paper presented to the European Society for Toxicology, Dublin, August 1981.Google Scholar
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    H. S. Sumano, The late pre-implantation surface coat change of the mouse embryo, Ph.D. Thesis, Trinity College, Dublin (1979).Google Scholar

Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • D. Michael Pugh
    • 1
  • Hector S. Sumano
    • 1
  1. 1.Department of Medicine and Pharmacology Faculty of Veterinary MedicineUniversity College DublinBallsbridge, Dublin 4Republic of Ireland

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