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Growth-Dependent and Age-Related Changes in the Free Amino Acid Pool of Human Diploid Fibroblasts

  • Yula Sambuy
  • Alan H. Bittles

Abstract

Free aminoacids are intermediates in protein catabolism. The size and composition of the intra-cellular pool is therefore in general determined by a balance between input, for example, from protein catabolism, uptake from the extra-cellular medium and de novo synthesis of non-essential aminoacids and removal, for incorporation into proteins, synthesis of other compounds (including the non-essential aminoacids) and degradation for energy production (1).

Keywords

Cellular Ageing Human Diploid Fibroblast Sulphosalicylic Acid Free Amino Acid Pool Cell Population Doubling 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • Yula Sambuy
    • 1
  • Alan H. Bittles
    • 1
  1. 1.Department of Human BiologyChelsea CollegeLondonUK

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