Use of Human Lymphoblastoid Cell Lines to Determine Cellular Hypersensitivity to Physical and Chemical Agents

  • Kenneth H. Kraemer


During the past decade, human lymphoblastoid cell lines have become recognized as providing a convenient source of material for studies of human genetic diseases [1–7]. Lymphocytes may be transformed with Epstein-Barr (EB) virus to produce immortal cell lines [8–10]. They are termed lymphoblastoid because of their morphological similarities to the immature lymphocytes called lymphoblasts.


Lymphoblastoid Cell Line Infectious Mononucleosis Xeroderma Pigmentosum Ataxia Telangiectasia Cockayne Syndrome 
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Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • Kenneth H. Kraemer
    • 1
  1. 1.Laboratory of Molecular CarcinogenesisNational Cancer InstituteBethesdaUSA

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