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Pathological Neurochemistry of Cerebrospinal Fluid

Neurotransmitters and Neuropeptides
  • Theodore A. Hare
  • James H. Wood

Abstract

Measurement of neuroactive substances in human cerebrospinal fluid (CSF) offers a unique opportunity for elucidating the pathology of neuropsychiatric disorders as well as for evaluating therapeutic approaches to these disorders. Human CSF is readily available and, in fact, offers the only source of such information from living patients that does not require brain biopsy with its associated morbidity. Studies of CSF effectively circumvent vagaries associated with extrapolation of data from autopsy tissue or from imperfect animal models.

Keywords

Schizophrenic Patient Essential Tremor Tardive Dyskinesia Neuropsychiatric Disorder Gaba Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Theodore A. Hare
    • 1
  • James H. Wood
    • 2
  1. 1.Department of Pharmacology, Jefferson Medical CollegeThomas Jefferson UniversityPhiladelphiaUSA
  2. 2.Cerebral Blood Flow Laboratories, Division of NeurosurgeryEmory University ClinicAtlantaUSA

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