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Structure of the Flavivirus Genome

  • Charles M. Rice
  • Ellen G. Strauss
  • James H. Strauss
Part of the The Viruses book series (VIRS)

Abstract

The flaviviruses were formerly classified as a genus in the family Togaviridae. They have now been elevated to family status, family Flaviviridae, in part because of differences in replication and assembly (Westaway, 1980) (Chapter 11) and in part because their genome structure is quite different from that of the alphaviruses (Rice et al., 1985) (compare with Chapter 3). With the determination of the complete nucleotide sequence of the yellow fever virus genome and a large portion of the Murray Valley encephalitis virus genome, it has become clear that these viruses represent a distinct group among the plus-stranded RNA viruses. This chapter will focus on the implications of these and other recent sequence data on flavivirus gene expression, replication, and evolution.

Keywords

West Nile Virus Encephalitis Virus Yellow Fever Nonstructural Protein Sindbis Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Charles M. Rice
    • 1
  • Ellen G. Strauss
    • 1
  • James H. Strauss
    • 1
  1. 1.Division of BiologyCalifornia Institute of TechnologyPasadenaUSA

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