Advertisement

Molecular Events in Lymphocyte Activation: Role of Nonhistone Chromosomal Proteins in Regulating Gene Expression

  • Janet M. Decker
  • John J. Marchalonis
Part of the Contemporary Topics in Molecular Immunology book series (CTI)

Abstract

The resting small lymphocyte and the plasma cell have the same genetic complement, but phenotypically they are at opposite ends of the spectrum of metabolic activity. Both the transformation from B lymphocyte to antibody producer and the transformation from T lymphocyte to effector cell (producing one of a multitude of factors of varying specificities and functions) are initiated by a binding event at the cell surface, which is followed approximately 24 hr later by the onset of DNA synthesis and the morphological changes we term blastogenesis. In the ensuing differentiation to plasma cell or T effector cell, memory cells are also created that can respond more rapidly to a second encounter with the same antigen.

Keywords

Peripheral Blood Lymphocyte Molecular Event Cyclic Nucleotide Lymphocyte Activation Human Peripheral Blood Lymphocyte 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Adkinson, N. F., Jr., Rosenberg, S. A., and Terry, W. D., 1974, J. Immunol. 112:1426. Allen, D., Auger, J., and Crumpton, M. J., 1972, Nature (London) New Biol. 236:23. Allfrey, V. G., Littau, V. C., and Mirsky, A. E., 1963, Proc. Natl. Acad. Sci. U.S.A. 49:414. Allfrey, V. G., Kam, J., Johnson, E. M., and Vidali, G., 1974, in: Control of Proliferation in Google Scholar
  2. Animal Cells (B. Clarkson and R. Baserga, eds.), p. 681, Cold Spring Harbor Laboratory, New York.Google Scholar
  3. Allfrey, V. G., Inoue, A., Karn, J., Johnson, E. M., Good, R. A., and Hadden, J. W., 1975, in: The structure and Function of Chromatin, Ciba Found. Symp., Vol. 28, p. 199, Elsevier, Amsterdam.Google Scholar
  4. Allwood, G., Asherson, G. L., Davey, M. J., and Goodford, P. J., 1971, Immunology 21: 509.PubMedGoogle Scholar
  5. Andersson, J., and Melchers, F., 1973 Proc. Natl. Acad. Sci. U.S.A. 70:416. Google Scholar
  6. Andersson, J., Sjoberg, O., and Möller, G., 1972 Transplant. Rev. 11:131. Google Scholar
  7. Atkinson, J. P., Wedner, H. J., and Parker, C. W., 1975, J. Immunol. 115:1023. Bach, F., and Hirschhorn, K., 1963, Exp. Cell Res. 32: 592.Google Scholar
  8. Barker, K. L., 1971 Biochemistry 10:284. Google Scholar
  9. Baserga, R., and Stein, G., 1971, Fed. Proc. Fed. Am. Soc. Exp. Biol. 30:1752. Basham, T. Y., and Waxdai, M. J., 1975, J. Immunol. 114: 5827.Google Scholar
  10. Baxter, J. D., Rousseau, G. G., Higgins, S. J., and Tomkins, G. M., 1973, in: The Biochemistry of Gene Expression in Higher Organisms (J. R. Pollak and J. W. Lee, eds.), p. 206, Australian and New Zealand Book Co., Sydney.Google Scholar
  11. Bekhor, I., Kung, G. M., and Bonner, J., 1969,J. Mol. Biol. 39:351. Google Scholar
  12. Benjamin, W., and Gellhorn, A., 1968 Proc. Natl. Acad. Sci. U.S.A. 59: 262. Google Scholar
  13. Berridge, M. J., 1975, in: Advances in Cyclic Nucleotides, Vol. 6 (P. Greengard and G. A. Robison, eds.), p. 1, Raven Press, New York.Google Scholar
  14. Blankenship, J., and Bresnick, E., 1974 Biochim. Biophys. Acta 340:218. Google Scholar
  15. Blitstein-Willinger, E., Schulz, G., and Diamantstein, T., 1976, Immunology 30:529. Boffa, L. C., Vidali, G., and Allfrey, V. G., 1976, Exp. Cell Res 98: 396.Google Scholar
  16. Bottoms, G. D., and Jungmann, R. A., 1973 Proc. Soc. Exp. Biol. Med. 144:83. Google Scholar
  17. Boume, H. R., Lichtenstein, L. M., Melmon, K. L., Henney, C. S., Weinstein, Y., and Shearer, G. M., 1974, Science 184: 19.CrossRefGoogle Scholar
  18. Brostrom, C. O., Hunkeler, F. L. and Krebs, E. G., 1971, J. Biol. Chem. 246:1961. Buell, D. N., and Fahey, J. L., 1969, Science 164: 1524.Google Scholar
  19. Burleson, D. G., and Sage, H. J., 1976 J. Immunol. 116:696. Google Scholar
  20. Busch, G I Yeoman, L. C., Taylor, C. W., and Busch, H., 1974 Physiol. Chem. Phys. 6:1. Busch, H., 1965 Histones and Other Nuclear ProteinsAcademic Press, New York. Google Scholar
  21. Byus, C. V., Klimpel, G. R., Lucas, D. O., and Russell, R. H., 1977 Nature (London) 268:63.Google Scholar
  22. Calkins, C. E., Ozer, H., and Waksman, B. H., 1975, Cell. Immunol. 18: 187.Google Scholar
  23. Chambon, P., Gissinger, F., Mandel, J. L., Kedinger, G., Gniazdowski, M., and Meihloc, M., 1970, Cold Spring Harbor Symp. Quant. Biol. 35: 693.CrossRefGoogle Scholar
  24. Chiu, J.-F., Craddock, C., Getz, S., and Hnilica, L. S., 1973, FEBS Lett. 33:247. Chiu, J.-F., Wang, S., Fujitani, H., and Hnilica, L. S., 1975, Biochemistry 14:4552. Coffey, R. G., Hadden, E. M., and Hadden, J. W., 1977,J. Immunol. 119:1387. Cone, R. E., 1976, J. Immunol 116: 847.Google Scholar
  25. Cone, R. E., 1977, in: The Lymphocyte: Structure and Function (J. J. Marchalonis, ed.), p. 565, Marcel Dekker, New York.Google Scholar
  26. Cooper, H. L., 1973, in: Drugs and the Cell Cycle (A. M. Zimmerman, G. M. Padille, and I. L. Cameron, eds.), p. 137, Academic Press, New York.Google Scholar
  27. Cooper, H. L., and Rubin, A. D., 1965 Blood 25:1014. Google Scholar
  28. Couch, R. M., and Anderson, K. M., 1973 Biochem. Biophys. Res. Commun. 50:478. Coutinho, A., Möller, G., Andersson, J., and Bullock, W. W., 1973 Eur. J. Immunol. 3:299. Cross, M. E., and Ord, M. G., 1971 Biochem. J. 124:241. Google Scholar
  29. Cuatrecasas, P., 1975, in: Advances in Cyclic Nucleotide Research, Voi. 5, (G. I. Drummond, P. Greengard, and G. A. Robison, eds.), p. 79, Raven Press, New York.Google Scholar
  30. Cullen, S. E., David, C. S., Schreffler, D. C., and Nathanson, S. G., 1974, Proc. Natl. Acad. Sci. U.S.A. 71: 648.PubMedCrossRefGoogle Scholar
  31. Decker, J. M., and Marchalonis, J. J., 1977a Biochem. Biophys. Res. Commun. 74:584 Decker, J. M., and Marchalonis, J. J., 1977b, in The Immune System: Genetics and Regulation (E. Sercarz, L. Herzenberg, and C. F. Fox, eds.), p. 719, Academic Press, New York. Google Scholar
  32. Decker, J. M., Wan, G. W., and Marchalonis, J. J., 1977, Biochem. Biophys. Res. Commun. 74: 1536.Google Scholar
  33. Defer, N., Kitzis, A., Kruh, J., Brahms, S., and Brahms, J., 1977, Nucleic Acids Research 4: 2293.PubMedCrossRefGoogle Scholar
  34. DeRubertis, F. R., Zenser, T. V., Adler, W. H., and Hudson, T., 1974, J. Immunol. 113:151. DiSabato, G., Chen, D., and Erickson, J. W., 1975 Cell. Immunol. 17:495. Google Scholar
  35. Douvas, A. S., Harrington, C. A., and Bonner, J., 1975, Proc. Natl. Acad. Sci. U.S.A. 72: 3902.PubMedCrossRefGoogle Scholar
  36. Edelman, G. M., 1976 Science 192:218. Google Scholar
  37. Elgin, S. C. R., and Weintraub, H., 1975 Annu. Rev. Biochem. 44:725. Google Scholar
  38. Faragó, A., Antoni, F., and Fâbiân, F., 1974, Biochim. Biophys. Acta 370:459. Felsenfeld, G., 1978, Nature 271: 115.Google Scholar
  39. Ferber, E., and Resch, K., 1973 Biochim. Biophys. Acta 296:335. Google Scholar
  40. Ferber, E., and Resch, K., 1977, in: The Lymphocyte: Structure and Function (J. J. Marchalonis, ed.), p. 593, Marcel Dekker, New York.Google Scholar
  41. Ferber, E.. dePasquale, G. G., and Resch, K., 1975, Biochim. Biophys. Acta 398:364. Ferguson, R. M., Schmidtke, J. R., and Simmons, R. L., 1976, J. Immunol. 116:627. Fisher, D. B., and Mueller, G. C., 1968, Proc. Natl. Acad. Sci. U.S.A. 60:1396. Fisher, D. B., and Mueller, G. C., 1971, Biochim. Biophys. Acta 248: 434.Google Scholar
  42. Freedman, M. H., Raff, M. C., and Gomperts, B., 1975,Nature (London) 225:378. Frenster, J. H., 1965, Nature (London) 206: 680.Google Scholar
  43. Frenster, J. H., Allfrey, V. G., and Mirsky, A. E., 1963, Proc. Natl. Acad. Sci. U.S.A. 50: 1026.Google Scholar
  44. Garel, A., and Axel, R., 1976 Proc. Natl. Acad. Sci. U.S.A. 73:3966. Google Scholar
  45. Garrard, W. T., and Bonner, J., 1974 J. Biol. Chem. 249:5570. Google Scholar
  46. Gerner, E. W., and Humphrey, R. M., 1973, Biochim. Biophys. Acta 231:117. Gery, I., and Waksman, B. H., 1972, J. Exp. Med. 136: 143.Google Scholar
  47. Gilmour, R. S., and Paul, J., 1969,J. Mol. Biol. 40:137. Google Scholar
  48. Gilmour, R. S., and Paul, J., 1975, in: Chromosomal Proteins and Their Role in the Regulation of Gene Expression (G. S. Stein and L. J. Kleinsmith, eds.), p. 19, Academic Press, New York.Google Scholar
  49. Gilmour, R. S., Windass, J. D., Affara, N., and Paul, J., 1975, J. Cell. Physiol. 85:449. Gmelig-Meyling, F., UytdelHaag, A. G. C. M., and Ballieux, R. E., 1977, Cell. Immunol. 33: 156.Google Scholar
  50. Goldberg, N. D., Haddox, M. K., Dunham, E., Lopez, C., and Hadden, J. W., 1974, in: Control of Proliferation in Animal Cells (B. Clarkson and R. Baserga, eds.), p. 609, Cold Spring Harbor Laboratory, New York.Google Scholar
  51. Goldberg, N. D., Haddox, M. K., Nicol, S. E., Glass, D. B., Sanford, C. H., Kuehl, F. A., Jr.,and Estensen, R., 1975, in: Advances in Cyclic Nucleotides Research,Vol. 5 (G. I.Google Scholar
  52. Drummond, P. Greengard, and G. A. Robison, eds.), p. 307, Raven Press, New York. Goodwin, G. H., Nicolas, R. H., and Johns, E. W., 1975a, Biochim. Biophys. Acta 405:280. Goodwin, G. H., Shooter, K. V., and Johns, E. W., 1975b, Eur. J. Biochem. 54:427. Gorski, J., and Gannon, F., 1976, Annu. Rev. Physiol. 38: 425.Google Scholar
  53. Greaves, M 1977 Nature (London) 265:681. Google Scholar
  54. Greaves, M, and Janossy, G., 1972 Transplant. Rev. 11:87. Google Scholar
  55. Greene, W. C., and Parker, C. W., 1975, Biochem. Biophys Re Commun. 65:456. Greene, W. C., Parker, C. M., and Parker, C. W., 1976, Cell. Immunol. 25: 74.Google Scholar
  56. Greengard, P., 1976 Nature (London) 260:101. Google Scholar
  57. Hadden, J. W., 1975 Ann. N. Y. Acad. Sci. 256:352. Google Scholar
  58. Hadden, J. W., Hadden, E. M., Haddox, M. K., and Goldberg, N. D., 1972, Proc. NatL Acad. Sci. U.S.A. 69: 3024.PubMedCrossRefGoogle Scholar
  59. Hadden, J. W., Hadden, E. M., Sadlik, J. R., and Coffey, R. G., 1976, Proc. Natl. Acad. Sci. U.S.A. 73: 1717.Google Scholar
  60. Haddox, M. K., Furcht, L. T., Gentry, S. R., Moser, M. E., Stephenson, J. H., and Goldberg, N. D., 1976, Nature (London) 262: 146.CrossRefGoogle Scholar
  61. Hancock, R., 1969, J. Mol. Biol. 40:457. Google Scholar
  62. Hausen, P., Stein, H., and Peters, H., 1969 Eur. J. Biochem. 9:542. Google Scholar
  63. Hayden, G. A., Crowley, G. M., and Jamieson, G. A., 1970, J. Biol. Chem. 245:5827. Henkart, P. A., and Fisher, R I., 1975, J. Immunol. 114: 710.Google Scholar
  64. Henney, C. S., and Bubbers, J. E., 1973, J. Immunol 111: 85.PubMedGoogle Scholar
  65. Hirschhorn, R., Troll, W., Brittinger, G., and Weissmann, G., 1969, Nature (London) 222: 1247.CrossRefGoogle Scholar
  66. How, K., and Wang, T. Y., 1969 Arch. Biochem. Biophys. 133:238. Google Scholar
  67. Huang, R. C., and Bonner, J., 1962, Proc. Natl. Acad. Sci. U.S.A. 48: 1216.PubMedCrossRefGoogle Scholar
  68. Huang, R. C., and Huang, P. C., 1969 J. Mol. Biol. 39: 365. Google Scholar
  69. Hunt, S. M., and Marchalonis, J. J., 1974, Biochem. Biophys. Res. Commun. 61:1227. Inoue, M., Kishimoto, A., Takai, Y., Nishizuka, Y., 1977, J. Biol. Chem. 252:7610. Javaherian, K., Liu, L. F., and Wang, J. C., 1978, Science 199: 1345.Google Scholar
  70. Jazwinski, S. M., Wang, J. L., and Edelman, G. M., 1976, Proc. Natl. Acad. Sci. U.S.A. 73: 2231.Google Scholar
  71. Jensen, E. V., and DeSombre, E. R., 1973 Science 182:126. Google Scholar
  72. Jensen, E. V., Mumata, M., Brechex, P. I., and DeSombre, E. R., 1971, in The Biochemistry of Steroid Hormone Action (R. M. S. Smellie, ed.), p. 133, Academic Press, New York. Johns, E. W., Goodwin, G. H., Walker, J. M., and Sanders, C., 1975, in: The Structure and Function of Chromatin, CIBA Found. Symp.,Vol. 28, p. 95, Elsevier, Amsterdam. Johnson, E. M., 1977, in: Advances in Cyclic Nucleotides,Vol. 8 (P. Greengard and G. A.Robison, eds.), p. 267, Raven Press, New York.Google Scholar
  73. Johnson, E. M., and Allfrey, V. G., 1972 Arch. Biochem. Biophys. 152:786. Google Scholar
  74. Johnson, E. M., and Hadden, J. W., 1975 Science 187:1198. Google Scholar
  75. Johnson, E. M., Kam, J., and Allfrey, V. G., 1974, J. Biol. Chem. 249: 4990.PubMedGoogle Scholar
  76. Johnson, E. M., Hadden J. W., Inoue, A., and Allfrey, V. G., 1975a, Biochemistry 14:3873. Johnson, E. M., Inoue, A., Crouse, L. J., Allfrey, V. G., and Hadden, J. W., 1975b, Biochem. Biophys. Res. Commun. 65: 714.Google Scholar
  77. Johnson, L. D., and Hadden, J. W., 1977 Nucleic Acids Research 4:4007. Google Scholar
  78. Jones, G., 1973 Cell. Immunol. 9:393. Google Scholar
  79. Jungmann, R. A., and Schweppe, J. S., 1972, J. Biol. Chem. 247:5535. Google Scholar
  80. Jungmann, R. A., Lee, S., and DeAngelo, A. B., 1975, in: Advances in Cyclic Nucleotide Research, Vol. 5 (G. I. Drummond, P. Greengard, and G. A. Robison, eds.), p. 281, Raven Press, New York.Google Scholar
  81. Kamiyama, M., and Dastugue, B., 1971, Biochem. Biophys. Res. Commun. 44:29. Kamiyama, M., and Wang, T. Y., 1971, Biochim. Biophys. Acta 228: 563.Google Scholar
  82. Kam, J., Johnson, E. M., Vidali, G., and Allfrey, V. G., 1974, J. Biol. Chem. 249:667. Karn, J., Vidali, G., Boffa, L. C., and Allfrey, V. G., 1977, J. Biol. Chem. 252:7307. Katagiri, T., Terao, T., and Osawa, T., 1976, J. Biochem. 79: 849.Google Scholar
  83. Kay, J. E., 1972 Exp. Cell Res 71:245.Google Scholar
  84. Kay, J. E., and Cooke, A., 1971, FEBS Lett. 16: 9.PubMedCrossRefGoogle Scholar
  85. Kay, J. E., and Cooper, H. L., 1969 Biochim. Biophys. Acta 186:62. Google Scholar
  86. Keller, R., 1975 Cell. Immunol. 17:542. Google Scholar
  87. Kemp, B. E., Froscio, M., Rogers, A., and Murray, A. W., 1975, Biochem. J. 145:241. Kishimoto, A., Takai, Y., and Nishizuka, Y., 1977, J. Biol. Chem. 252: 7449.Google Scholar
  88. Kishimoto, T., Miyake, T., Nishizawa, Y., Watanabe, T., and Yamamura, Y., 1975, J. ImmunoL 115: 1179.PubMedGoogle Scholar
  89. Kishimoto, T., Nishizawa, Y., Kikutani, H., and Yamamura, Y., 1977, J. Immunol. 118: 2027.PubMedGoogle Scholar
  90. Kleinsmith, L. J., 1973, J. Biol. Chem. 248: 5648.Google Scholar
  91. Kleinsmith, L. J., 1975a, in: Chromosomal Proteins and Their Role in the Regulation of Gene Expression (G. S. Stein and L. J. Kleinsmith, eds.), p. 45, Academic Press, New York.Google Scholar
  92. Kleinsmith, L. J., 1975bJ. Cell. Physiol. 85:459. Google Scholar
  93. Kleinsmith, L. J., and Allfrey, V. G., 1969, Biochim. Biophys. Acta 175:123. Kleinsmith, L. J., Allfrey, V. G., and Mirsky, A. E., 1966, Science 154: 780.Google Scholar
  94. Kleinsmith, L. J., Heidema, J., and Carroll, A., 1970 Nature (London) 226:1025. Kleinsmith, L. J., Stein, J., and Stein, G., 1975, in Chromosomal Proteins and Their Role in the Regulation of Gene Expression (G. S. Stein and L. J. Kleinsmith, eds.), p. 59,Academic Press, New York.Google Scholar
  95. Kleinsmith, L. J., Stein, J., and Stein, G., 1976, Proc. Natl. Acad. Sci. USA 73:1174. Kornberg, R. D., 1974, Science 184: 868.Google Scholar
  96. Kostraba, N. C., and Wang, T. Y., 1972 Biochim. Biophys. Acta 262:169. Google Scholar
  97. Krishnaraj, R., and Talwar, G. P., 1973, J. Immunol. 111: 1010.Google Scholar
  98. Kruh, J., Courtois, Y., Dastugue, B., Defer, N., Gibson, K., Kamiyama, M., and Tichonicky, L., 1975, in: Regulation of Growth and Differentiated Function in Eukaryote Cells (G. P. Talwar, ed.), p. 139, Raven Press, New York.Google Scholar
  99. Lauf, P. K., 1975 Biochim. Biophys. Acta 415:173. Google Scholar
  100. Lazo, J. S., Prasad, K. N., and Ruddon, R. W., 1976 Exp. Cell Res. 100:41. Google Scholar
  101. Levy, R., and Rosenberg, S. A., 1972, J. Immunol. 108: 1073.Google Scholar
  102. Levy, R., and Rosenberg, S. A., 1973 Cell. Immunol. 7:92. Google Scholar
  103. Levy, R., Levy, S., Rosenberg, S. A., and Simpson, R. T., 1973 Biochemistry 12: 224. Liew, C. C., and Chan, P. K., 1976 Proc. Natl. Acad. Sci. U.S.A. 73:3458. Google Scholar
  104. Ling, N. R., and Kay, J. E., 1975 Lymphocyte StimulationNorth-Holland, Amsterdam. Loeb, J. E., and Creuzet, C., 1970 Bull. Soc. Chim. Biol. 52:1007. Google Scholar
  105. Lucas, D. O., Shohet, S. B., and Merler, E., 1971, J. Immunol. 106: 768.Google Scholar
  106. Lucas, Z. J., 1967 Science 156:1237. Google Scholar
  107. Luckasen, J. R., White, J. G., and Kersey, J. H., 1974, Proc. Natl. Acad. Sci. U.S.A. 71:5088. Google Scholar
  108. Lyle, L. R., and Parker, C. W., 1974 Biochemistry 13:5415. Google Scholar
  109. MacGillvray, A. J., Carroll, D., and Paul, J., 1971, FEBS Lett. 13: 204.CrossRefGoogle Scholar
  110. MacManus, J. P., Whitfield, J. F., Boynton, A. L., and Rixon, R. H., 1975, in: Advances in Cyclic Nucleotide Research, Vol. 5 (G. I. Drummond, P. Greengard, and G. A. Robison, eds.), p. 719, Raven Press, New York.Google Scholar
  111. Maino, V. C., Green, N. M., and Crumpton, M. J., 1974, Nature (London) 251:324. Makman, M. H., 1971, Proc. Natl. Acad. Sci. U.S.A. 68: 885.Google Scholar
  112. Marchalonis, J. J., 1976, in: Contemporary Topics in Molecular Immunology (H. N. Eisen and R. A. Reisfeld, eds.), Vol. 5, p. 125, Plenum Press, New York.Google Scholar
  113. McClain, D. A., and Edelman, G. M., 1976, J. Exp. Med. 144:1494. Google Scholar
  114. Melcher, U., and Uhr, J. W., 1977 Biochemistry 16:145. Google Scholar
  115. Melchers, F., and Andersson, J., 1973 Transplant. Rev. 14:76. Google Scholar
  116. Mendelsohn, J., Skinner, A., and Kornfeld, S., 1971, J. Clin. Invest. 50: 818.Google Scholar
  117. Michell, R. H., 1975 Biochim. Biophys Acta 415:81. Google Scholar
  118. Milner, S. M., 1977 Nature (London) 268:441. Google Scholar
  119. Niedermeir, W., Schrohenloher, R. E., and Hurst, M., 1972, J. Immunol. 108:346. Nilsson, S. F., and Waxdal, M. J., 1976, Biochemistry 15: 2698.Google Scholar
  120. Nimmo, H. G. and Cohen, P., 1977, in: Advances in Cyclic Nucleotide Research, Vol. 8, (P. Greengard and G. A. Robison, eds.), p. 145, Raven Press, New York.Google Scholar
  121. Nishizawa, Y., Kishimoto, T., Kikutani, H., and Yamamura, Y., 1977, J. Exp. Med. 146: 653.PubMedCrossRefGoogle Scholar
  122. Novogrodsky, H., 1972, Biochim. Biphys. Acta 266: 343.CrossRefGoogle Scholar
  123. Olson, M. O. J., and Busch, H., 1974, in: The Cell Nucleus, Vol. 3 (H. Busch, ed.), p. 211, Academic Press, New York.Google Scholar
  124. Olson, M. O. J., Starbuck, W. C., and Busch, H., 1974, in: The Molecular Biology of Cancer (H. Busch, ed.), p. 309, Academic Press, New York.Google Scholar
  125. O’Malley, B. W., and Means, A. R., 1974, in: The Cell Nucleus, Vol. 3 (H. Busch, ed.), p. 379, Academic Press, New York.Google Scholar
  126. O’Malley, B. W., Spelsberg, T. C., Schrader, W. T., Chytil, F., and Steggles, A. W., 1972, Nature (London) 235: 141.CrossRefGoogle Scholar
  127. O’Malley, B. W., Woo, S. L. C., Harris, S. E., Rosen, J. M., and Means, A. R., 1975, J. Cell. Physiol. 85: 343.CrossRefGoogle Scholar
  128. Oppenheim, J. J., and Rosenstreich, D. L., 1976, Prog. Allergy 20: 65.PubMedCrossRefGoogle Scholar
  129. Oppenheimer, J. H., Schwartz, H. L., Surks, M. I., Koerner, D., and Dillmann, W. H., 1976, in: Recent Progress in Hormone Research, Vol. 32 (R. O. Greep, ed.), p. 529, Academic Press, New York.Google Scholar
  130. Ozato, K., Adler, W. H., and Ebert, J. D., 1975, Cell. Immunol. 17: 532.PubMedCrossRefGoogle Scholar
  131. Painter, R. G., and White, A., 1976, Proc. Natl. Acad. Sci. U.S.A. 73: 837.PubMedCrossRefGoogle Scholar
  132. Parker, C. W., 1974a, Biochem. Biophys. Res. Commun. 61: 1180.Google Scholar
  133. Parker, C. W., 1974b, in: Cyclic AMP, Cell Growth and the Immune Response (W. Braun, L. Lichtenstein, and C. Parker, eds.), p. 35, Springer-Verlag, New York.Google Scholar
  134. Parker, C. W., Smith, J. W., and Steiner, A. L., 1971, Int. Arch. Allergy Appl. Immunol. 41: 40.PubMedCrossRefGoogle Scholar
  135. Parkhouse, R. M. E., Janossy, G., and Greaves, M. F., 1972, Nature (London) New BioL 235: 21.CrossRefGoogle Scholar
  136. Paul, J., and Gilmour, R. S., 1968, J. Mol Biol. 34: 305.PubMedCrossRefGoogle Scholar
  137. Peters, J. H., and Hausen, P., 1971a, Eur. J. Biochem. 19: 502.PubMedCrossRefGoogle Scholar
  138. Peters, J. H., and Hausen, P., 1971b, Eur. J. Biochem. 19: 509.PubMedCrossRefGoogle Scholar
  139. Peterson, J. L., and McConkey, E. H., 1976, J. Biol. Chem. 251: 548.PubMedGoogle Scholar
  140. Platz, R. D., Grimes, S. R., Hard, G., Meistrich, M. L., and Hnilica, L. S., 1975, in: Chromosomal Proteins and Their Role in the Regulation of Gene Expression (G. S. Stein and L. J. Kleinsmith, eds.), p. 67, Academic Press, New York.Google Scholar
  141. Pogo, B. G. T., 1972, J. Cell Biol. 53: 635.PubMedCrossRefGoogle Scholar
  142. Pogo, B. G. T., Allfrey, V. G., and Minsky, A. E., 1966, Proc. Natl. Acad. Sci. U.S.A. 55:805. Google Scholar
  143. Putnam, F. W., Florent, G., Paul, C., Shinoda, T., and Shimizu, A., 1973, Science 182:287. Quastel, M. R., and Kaplan, J. G., 1970, Exp. Cell Res. 63: 230.Google Scholar
  144. Rasmussen, H., Jensen, P., Lake, W., Friedmann, N., and Goodman, D. B. P., 1975, in: Advances in Cyclic Nucleotide Research, VoL 5 (G. L Drummond, P. Greengard, and G. A. Robison, eds.), p. 375, Raven Press, New York.Google Scholar
  145. Ravid, A., and Novogrodsky, A., 1976, Exp. Cell Res. 97: 1.PubMedCrossRefGoogle Scholar
  146. Resch, K., Gelfand, E. W., Hanson, K., and Ferber, E., 1972, Eur. J. Immunol. 2:598. Rickwood, D., Riches, P. G., and MacGillivray, A. J., 1973, Biochim. Biophys. Acta 299: 162.Google Scholar
  147. Robison, G. A., Butcher, R. W., and Sutherland, E. W., 1971, Cyclic AMP, Academic Press, New York.Google Scholar
  148. Rosenberg, S. A., and Levy, R., 1972, J. Immunol. 108: 1105.Google Scholar
  149. Rosentreich, D. L., Farrar, J. J., and Dougherty, S., 1976, J. Immunol 116:131. Rovera, G., and Baserga, R., 1971,J. Cell. Physiol. 77: 201.Google Scholar
  150. Rubin, A. D., and Cooper, H. L., 1965 Proc. Natl. Acad. Sci. U.S.A. 54:469. Google Scholar
  151. Samuels, H. H., and Tsai, J. S., 1973 Proc. Natl. Acad. Sci. U.S.A. 70:3488. Google Scholar
  152. Scheid, M. P., Hoffman, M. K., Komuro, K., Hämmerling, U., Abbot, J., Boyse, E. A., Cohen, G. H., Hooper, J. A., Schulof, R. S., and Goldstein, A. L., 1973, J. Exp. Med. 138: 1027.Google Scholar
  153. Schmidtke, J. R., and Hatfield, S., 1976 J. Immunol. 116:357. Google Scholar
  154. Schmidtke, J. R., and Najarian, J. S., 1975, J. Immunol. 114: 742.Google Scholar
  155. Schmidt-Ullrich, R., Wallach, D. F. H., and Hendricks, J., 1976, Biochim. Biophys. Acta 443: 587.PubMedCrossRefGoogle Scholar
  156. Schreiner, G. F., and Unanue, E. R., 1976 Adv. Immunol. 24:37. Google Scholar
  157. Schumm, D. E., Morris, H. P., and Webb, T. E., 1974 Eur. J. Cancer 10:107. Google Scholar
  158. Segrest, J. P., and Feldmann, R. J., 1974 J. Mol. Biol. 87:853. Google Scholar
  159. Sekeris, C. E., and Schmid, W., 1973, in: The Biochemistry of Gene Expression in Higher Organisms (J. K. Pollak and J. W. Lee, eds.), p. 225, Australian and New Zealand Book Co., Sydney.Google Scholar
  160. Sell, S., 1974 Cell. Immunol. 12:119. Google Scholar
  161. Sell, S., and Gell, P. G. H., 1965 J. Exp. Med 122:423. Google Scholar
  162. Sell, S., and Sheppard, H. W., Jr., 1974 Exp. Cell Res. 84:153. Google Scholar
  163. Sell, S., Rowe, D. S., and Gell, P. G. H., 1965 J. Exp. Med. 122:823. Google Scholar
  164. Sharma, O. K., and Loeb, L. A., 1973, Biochim. Biophys. Res. Commun. 50:172. Shea, M., and Kleinsmith, L. J., 1973, Biochem. Biophys. Res. Commun. 50:473. Shek, P. N., Chou, C.-T., Dubinski, S., and Cinader, B., 1974, Int. Arch. Allergy Appl.Immunol. 46: 753.Google Scholar
  165. Shelton, K. R., and Allfrey, V. G. 1970 Nature (London) 228:132. Google Scholar
  166. Sheppard, H. W., Jr., Redelman, D., and Sell, S., 1976 Cell. Immunol. 24:34. Google Scholar
  167. Siebert, G., Ord, M. G., and Stocken, L. A., 1971 Biochem. J. 122:721. Google Scholar
  168. Silver, L. M., and Elgin, S. C. R., 1976 Proc. Natl. Acad. Sci. U.S.A. 73:423. Google Scholar
  169. Smith, J. W., Steiner, A. L., Newberry, W. M., Jr., and Parker, C. W., 1971, J. Clin. Invest. 50. 432.PubMedCrossRefGoogle Scholar
  170. Snary, D., Goodfellow, P., Hayman, M. J., Bodmer, W. F., and Crumpton, M. J., 1970, Nature (London) 247: 457.CrossRefGoogle Scholar
  171. Sorg, C., 1975 Eur. J. Biochem. 55:423. Google Scholar
  172. Sorg, C., and Bloom, B. R., 1973 J. Exp. Med. 137:148. Google Scholar
  173. Spelsberg, T., and Hnilica, L., 1970, Biochem. J. 120: 435.PubMedGoogle Scholar
  174. Spelsberg, T. C., Hnilica, L. S., and Ansevin, A. T. 1971 Biochim. Biophys. Acta 228:550. Spelsberg, T. C., Webster, R., and Pikier, G. M., 1975, in Chromosomal Proteins and Their Role in the Regulation of Gene Expression (G. S. Stein and L. J. Kleinsmith, eds.), p. 153, Academic Press, New York.Google Scholar
  175. Spivak, J. L., 1976 Blood 47:581. Google Scholar
  176. Stein, G., and Baserga, R., 1970,J. Biol. Chem. 245:6097. Google Scholar
  177. Stein, G. S., and Borun, T. W., 1972, J. Cell Biol. 52:292. Google Scholar
  178. Stein, G. S., Spelsberg, T. C., and Kleinsmith, L. J., 1974 Science 183:817. Google Scholar
  179. Stein, G., Park, W., Thrall, C., Mans, R., and Stein, J., 1975a, Nature (London) 257:764. Stein, G., Stein, J., Thrall, C., and Park, W., 1975b, in: Chromosomal Proteins and Their Role in the Regulation of Gene Expression (G. S. Stein and L. J. Kleinsmith, eds.), p. 1, Academic Press, New York.Google Scholar
  180. Symons, D. B. A., Lay, C. A., and MacDonald, A. N., 1977, Int. Arch. Allergy App. Immunol. 54: 67.CrossRefGoogle Scholar
  181. Takai, Y., Kishimoto, A., Inoue, M., and Nishizuka, Y., 1977, J. Biol. Chem. 252:7603. Takeda, M., Yamamura, H., and Ohga, Y., 1971, Biochem. Biophys. Res. Commun. 42:103. Tashiro, T., and Kurokawa, M., 1975, Eur. J. Biochem. 60: 569.Google Scholar
  182. Teng, C. S., Teng, C. T., and Allfrey, V. G., 1971, J. Biol. Chem. 246: 3597.PubMedGoogle Scholar
  183. Toyoshima, S., Iwata, M., and Osawa, T., 1976 Nature (London) 264:447. Google Scholar
  184. Tsuboi, A., and Baserga, R., 1972, J. Cell. Physiol. 80:107. Google Scholar
  185. Turkington, R. W., and Majumder, G. C., 1975 J. Cell. Physiol. 85:495 van den Broek, H. W. J., Noodén, L. D., Sevall, J. S., and Bonner, J., 1973, Biochemistry 12:229. Google Scholar
  186. Vidali, G., Boffa, L. C., Littau, V. C., Allfrey, K. M., and Allfrey, V. G., 1973, J. Biol. Chem. 248: 4065.PubMedGoogle Scholar
  187. Vidali, G., Boffa, L. C., and Allfrey, V. G., 1977 Cell 12:409. Google Scholar
  188. Walsh, F. S., and Crumpton, M. J., 1977, Nature (London) 269: 307.CrossRefGoogle Scholar
  189. Wang, J. L., Gunther, G. R., and Edelman, G. M., 1975 J. Cell Biol. 66:128. Google Scholar
  190. Wang, T. Y., 1967 J. Biol. Chem. 242:1220. Google Scholar
  191. Wang, T. Y., and Kostraba, N. C., 1975, in: Chromosomal Proteins and Their Role in the Regulation of Gene Expression (G. S. Stein and L. J. Kleinsmith, eds.), p. 35, Academic Press, New York.Google Scholar
  192. Warner, N. L., 1974 Adv. Immunol. 19:67. Google Scholar
  193. Warr, G. W., and Marchalonis, J. J., 1976 Immunochemistry 13:753. Google Scholar
  194. Watson, J., 1974, in: The Immune System: Genes, Receptors, Signals, (E. E. Sercarz, A. R. Williamson, and C. F. Fox, eds.), p. 511, Academic Press, New York.Google Scholar
  195. Watson, J., Epstein, R., and Cohn, M., 1973 Nature (London) 246:405. Google Scholar
  196. Weber, Th.H., Skoog, V. T., Mattsson, A., and Lindahl Kiessling, K., 1974, Exp. Cell Res. 85:351 Google Scholar
  197. Wedner, H. J., and Parker, C. W., 1975, Biochem. Biophys. Res. Commun. 62:808. Wedner, H. J., and Parker, C. W., 1976, Prog. Allergy 20: 195.Google Scholar
  198. Wedner, H. J., Danker, R., and Parker, C. W., 1975 J. Immunol. 115:1682. Google Scholar
  199. Weintraub, H., and Groudine, M., 1976, Science 193: 848.Google Scholar
  200. Weisenthal, L. M. and Ruddon, R W., 1972, Cancer Res. 32: 1009.PubMedGoogle Scholar
  201. Weisenthal, L. M., and Ruddon, R. W., 1973 Cancer Res. 33:2923. Google Scholar
  202. Whitney, R. B., and Sutherland, R. M., 1972 Cell. Immunol. 5:137.Google Scholar
  203. Yamamoto, I., and Webb, D. R., 1975 Proc. Natl. Acad. Sci. U.S.A. 72:2320. Google Scholar

Copyright information

© Springer Science+Business Media New York 1978

Authors and Affiliations

  • Janet M. Decker
    • 1
  • John J. Marchalonis
    • 1
  1. 1.Cancer Biology ProgramNCI Frederick Cancer Research CenterFrederickUSA

Personalised recommendations