H-2 Antigens pp 157-168 | Cite as

Toward an Understanding of the Biochemical Nature of H-2 Molecules: A Historical Perspective

  • Stanley G. Nathenson
Part of the NATO ASI Series book series (NSSA, volume 144)


As part of an historical perspective of the development of our knowledge of the H-2 genes and products, this paper presents a brief, selected, personal account of those studies from my laboratory which were carried out with the objective to understand the biochemical nature of H-2 molecules. This work was performed with the goal of relating the structural features of what are now called class I MHC molecules to their biological function, in addition to expanding our understanding of the genetic organization and diversity of the H-2 region genes.


Cyanogen Bromide Antigenic Activity Biochemical Nature Transplantation Antigen Monospecific Antiserum 


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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • Stanley G. Nathenson
    • 1
  1. 1.Department of Microbiology and Immunology and Department of Cell BiologyAlbert Einstein College of MedicineBronxUSA

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