Advertisement

Proliferation and Morphology of Ascitic Cells as a Function of Age In Cell Culture

  • A. Balázs
  • L. Holczinger
  • I. Fazekas
  • G. Turi
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 53)

Abstract

The population kinetics of ascitic cells, in vivo and in vitro cultivated ones, are similar in their main features. Following the lag and log periods of growth, the proliferation of ascitic cells is limited by stationary phase, too. The prolongation of their generation time, the decrease of the growth fraction, DNA synthesis and mitotic index (MI), as well as the accumulation of specific G1 and G2 inhibitors, characterize this period (1–6).

Keywords

Lipid Droplet Mitotic Index Ascitic Fluid Glycogen Content Binucleate Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Wiebel, F. and Baserga, R. 1968. Cell proliferation in newly transplanted Ehrlich ascities tumor cells. Cell Tissue Kinet. 1: 273.Google Scholar
  2. 2.
    Frindel, E., Valleron, A.J. and Vassort, F. 1969. Proliferation kinetics of an experimental ascites tumor of the mouse. Cell Tissue Kinet. 2; 51.Google Scholar
  3. 3.
    Dombernowsky, P., Bichel, P. and Hartmann, N.R. 1973. Cyto-kinetic analysis of the JB-1 ascites tumor at different stages of growth. Cell Tissue Kinet, 6: 347.Google Scholar
  4. 4.
    Burns, E.R. 1969. On the failure of self-inhibition of growth in tumors® Growth 33: 25.Google Scholar
  5. 5.
    Bichel, P. 1971. Autoregulation of ascites tumour growth by inhibition of the G1 and G2 phase. Europ. J. Cancer 7: 349.Google Scholar
  6. 6.
    Bichel,’P. 1973. Self-limitation of ascites tumor growth: A possible chalone regulation. Nat. Cancer Inst. Monograph 38: 197.Google Scholar
  7. 7.
    Gâl, Fa, Somfai, S. and Szentirmai, Z. 1973. Transplantable myeloid rat leukemia induced by 7, 12-dimethylbenz(a)anthra-cene. Acta Haematol. 49: 281.Google Scholar
  8. 8.
    Holczinger, L. and’Gfil, F. Glycogen storgae in cells of an ascites rat leukaemia. Z.Krebsforsch. in pressoGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1975

Authors and Affiliations

  • A. Balázs
    • 1
    • 2
  • L. Holczinger
    • 1
    • 2
  • I. Fazekas
    • 1
    • 2
  • G. Turi
    • 1
    • 2
  1. 1.The Institue of Experimental MedicineHungarian Academy of SciencesBudapestHungary
  2. 2.Institute of OncopathologyBudapestHungary

Personalised recommendations