Ultrastructure of in Vitro Aged Chick Embryo Cell Cultures in Relation to Viral Infection

  • Fedor Cǐampor
  • Helena Líbíková
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 53)


The ultrastructure of young uninfected and infected with herpes simplex virus chick embryo cells was compared with that aged cells. In contrast to the nuclei of young chick embryo cells 24 hr after infection, the aged chick embryo cells 24 hr after infection presented very expressive blocks of perinuclear chromatin. The nucleoplasm contains forming naked HSV particles. The lesions seen are dilation of the perinuclear cisternae, dilatation of rough endoplasmic reticulum cisternae and formation of multilamellar bodies. The moderate swellings of the mitochondria with violation of cristae arrangement and losing of mitochondrial matrix were observed. In contrast to the cytoplasm of young infected cells no formation of crystal-like arrangement of cytoplasmic ribosome tetrads occurs.


Herpes Simplex Virus Rough Endoplasmic Reticulum Young Culture Abortive Infection Chick Embryo Cell 


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Copyright information

© Springer Science+Business Media New York 1975

Authors and Affiliations

  • Fedor Cǐampor
    • 1
  • Helena Líbíková
    • 1
  1. 1.Institute of VirologySlovak Academy of ScienceBratislavaCzechoslovakia

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