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Morphometrical and Mathematical Analysis of the Ageing Changes of the Muscle-Connective-Tissue-Relation in Smooth Muscles

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Book cover Cell Impairment in Aging and Development

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 53))

Abstract

The effects of ageing on the muscle-connective tissue relation­ships of smooth muscles have been studied by the point counting method of Chalkley and Haug. Sections of the small intestinal walls of 60 persons as well as of the ciliary bodies of 55 persons of all age groups were available for these studies.’ The morphometric results were tested by statistical methods, and linear regression functions as well as exponential functions of the form y = Ao + A1ejt were adapted to them. We were especially interested in finding answers to the following three questions:

  1. 1.

    What is the rate of this particular process of ageing in the various periods of life?

  2. 2.

    Are there any specific sex differences in this respect?

  3. 3.

    What is the primary event in this connection, the decrease in muscle cells or the increase of connective tissue?

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References

  1. Blume, R. and Buch, Ch. 1967. Ein Beitrag zum Trefferverfahren nach Chalkley. Z. mikr.-anat. Forsch. 76: 26.

    Google Scholar 

  2. Blume, R., Rother, P. and Lochner, M. 1971. Lineare Differentialgleichungen zur Beschreibung der histologischen Biomorphose des menschlichen Ziliarmuskels. Z. Alternsforschung 23: 235.

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  3. Chalkley, H.W. 1943. Method for quantitative morphologic analysis of tissue. J. Nat. Cancer Inst. 4:’47.

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  4. Haug, H. 1955. Die Treffermethode, ein Verfahren zur quantitativen Analyse im histologischen Schnitt. Z. Anat. Entw. Gesch. 118: 302.

    Google Scholar 

  5. Haug, H. 1962. Bedeutung und Grenzen der quantitativen,ieß-’ methoden in der Histologie. In: Medizinische Grundlagen-forschung Bd. IV von K.F.’ Bauer, Thieme Stuttgart.

    Google Scholar 

  6. Jahn, K., Leutert, G. and Rotzsch, W. 1971. Altersabhängige, morphologische und biochemische Untersuchungen der menschl. Prostate, Z. Alternsforsch. 23: 323.

    Google Scholar 

  7. Rother, P. 1970. Morphometrische Untersuchungen zur Biomorphose menschlicher Glandulae parathyreoideae Gegenbaurs. Morph. Jahrb. 115: 231.

    Google Scholar 

  8. Rother, P. 1970. Zur Geschlechtsdifferenz der Biomorphose menschlicher Glandulae parathyreoideae. Morph. Jahrb. 115: 231.

    Google Scholar 

  9. Rother, P,, Blume, R., Friedrich, H. and Lochner, M, 1971. Die Veränderung der Muskel-Bindegewebs-Relation des Muskulus ciliaris im Laufe des Lebens, Anat. Anzeiger 129: 322.

    Google Scholar 

  10. Rother, P. and Friedrich, H. 1971. Regressionsanalysen zur Beschreibung morphologischer Alternsprozesse® Biolog. Rundschau 9: 172

    Google Scholar 

  11. Rother, P. and Leutert, G. 1965. -;Die Altersveränderung des Ciliark®rpers, Albrecht von Graefes. Arch. klin. exp. OpÏithall 168: 136.

    Google Scholar 

  12. Rother, P., Walther, M., Scheller, G. and Blume, R. 1973. Morphometrische Untersuchungen zur histologischen Biomorphose der Wand des Dünndarmes. Zuikoosk. und Torsch. 87: 97.’

    Google Scholar 

  13. Scheller, G., Rother, P. and Walther, M. 1972. Uber die, Veränderungen von Zellgröße,’Kerngröße und Kern-Plasma-Relation beim Altern von Epithelzellen und Epithelgewebe Z. mikr.-anat. Forsch. 85: 123.

    Google Scholar 

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© 1975 Springer Science+Business Media New York

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Rother, P., Leutert, G. (1975). Morphometrical and Mathematical Analysis of the Ageing Changes of the Muscle-Connective-Tissue-Relation in Smooth Muscles. In: Cristofalo, V.J., Holečková, E. (eds) Cell Impairment in Aging and Development. Advances in Experimental Medicine and Biology, vol 53. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0731-1_37

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  • DOI: https://doi.org/10.1007/978-1-4757-0731-1_37

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0733-5

  • Online ISBN: 978-1-4757-0731-1

  • eBook Packages: Springer Book Archive

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