Morphometrical and Mathematical Analysis of the Ageing Changes of the Muscle-Connective-Tissue-Relation in Smooth Muscles

  • Paul Rother
  • Gerald Leutert
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 53)


The effects of ageing on the muscle-connective tissue relation­ships of smooth muscles have been studied by the point counting method of Chalkley and Haug. Sections of the small intestinal walls of 60 persons as well as of the ciliary bodies of 55 persons of all age groups were available for these studies.’ The morphometric results were tested by statistical methods, and linear regression functions as well as exponential functions of the form y = Ao + A1ejt were adapted to them. We were especially interested in finding answers to the following three questions:
  1. 1.

    What is the rate of this particular process of ageing in the various periods of life?

  2. 2.

    Are there any specific sex differences in this respect?

  3. 3.

    What is the primary event in this connection, the decrease in muscle cells or the increase of connective tissue?



Connective Tissue Regression Function Ciliary Body Ciliary Muscle Point Counting Method 
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Copyright information

© Springer Science+Business Media New York 1975

Authors and Affiliations

  • Paul Rother
    • 1
  • Gerald Leutert
    • 1
  1. 1.Anatomisches InstitutKarl-Marx-UniversitätLeipzigDDR

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