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Acid protease and its Proenzyme from Human Seminal Plasma

  • Pintip Ruenwongsa
  • Montri Chulavatnatol
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 92)

Abstract

An acid protease with an optimum pH of 2.5 was first described in human seminal plasma as pepsin and pepsinogen (1), but had not been purified or characterized. Recently, we have purified the acid protease and its proenzyme from human seminal plasma (2,3). In many respects, the properties of seminal plasma acid protease are similar to those of gastric pepsin. Since the proenzyme is more stable than the active enzyme in alkaline solution and can be converted into its active form in acidic solution, the acid protease is likely to exist in seminal plasma, at the physiological pH around 7.5 (4), in proenzyme form.

Keywords

Seminal Plasma Acid Protease Female Reproductive Tract Cervical Mucus Vaginal Fluid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1977

Authors and Affiliations

  • Pintip Ruenwongsa
    • 1
  • Montri Chulavatnatol
    • 1
  1. 1.Department of Biochemistry, Faculty of ScienceMahidol UniversityBangkokThailand

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