Normal and Abnormal Limbic System Mechanisms of Emotive Biasing

  • Robert E. Adamec


In 1969 Goddard, McIntyre & Leech demonstrated that a permanent change in limbic system excitability could be induced by repeated electrical stimulation, and termed the process kindling. Alterations in excitability appear as reductions in electrical threshold for evocation of motor seizures and in threshold for evocation of electrographically recorded seizures without motor involvement (Racine, 1972a). An apparent increase in transsynaptic conduction between limbic system structures of both epileptic (Racine, 1972b; Adamec, 1975a) and non epileptically-induced neural activity (Racine, Gartner & Burnham, 1972; Douglas & Goddard, 1975) accompanies the alterations of epileptic excitability.


Defensive Response Ventral Hippocampus Predatory Attack Motor Seizure Mean Square 
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© Springer Science+Business Media New York 1978

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  • Robert E. Adamec

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