Papillomavirus Cloning Vectors

  • Daniel DiMaio
Part of the The Viruses book series (VIRS)


The papillomaviruses are proving to be valuable tools for transferring genes into living mammalian cells because the viral DNA can be used to establish permanent cell lines containing the transferred genes as unrearranged, extrachromosomal DNA molecules. This use of these viruses may help elucidate the function and regulation of eukaryotic genes and may enable the production of gene products that would otherwise be difficult to obtain. Bovine papillomavirus type 1 is the only papillomavirus to be exploited so far as a cloning vector, but it is likely that similar vectors will also be derived from DNA of other papillomaviruses.


C127 Cell Mouse Cell Mouse Mammary Tumor Virus Virus Surface Antigen Vesicular Stomatitis Virus Glycoprotein 


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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Daniel DiMaio
    • 1
  1. 1.Department of Human GeneticsYale University School of MedicineNew HavenUSA

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