Pituitary Secretory Activity and Endocrinophagy
Recent advances in quantitative electron-microscopic autoradiography, cytochemistry, and immunoassay techniques have provided more precise information on the location and kinetics of the intracellular processing of adenohypophyseal hormones than has been possible previously using other systems. These studies have elucidated many of the biochemical and morphological pathways in the synthesis, intracellular transport, release, and endocrinophagy of adenohypophyseal hormones. The growth-hormone (GH) cell or somatotroph has served as the model for our laboratory investigations on the mechanism(s) by which secretagogues stimulate hormone synthesis and release from the adenohypophysis.
KeywordsLuteinizing Hormone Secretory Granule Rough Endoplasmic Reticulum Anterior Pituitary Golgi Complex
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