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The Pattern of LH Release of Rat Pituitary Glands during Long-Term Exposure to LH-RH in Vitro

  • Jurrien de Koning
  • Hannie A. M. J. van Dieten
  • G. Peter van Rees
Part of the Biochemical Endocrinology book series (BIOEND)

Abstract

During continuous exposure of pituitary glands of intact rats to synthetic luteinizing hormone-releasing hormone (LH-RH) in vitro (de Koning et al., 1976a,b, 1978a) and in vivo (Schuiling and Zürcher, 1975; Blake, 1976; Vilchez-Martinez et al., 1976; Schuiling et al., 1976), three phases in the luteinizing hormone (LH)-releasing patterns can be distinguished. Initially, the rate of LH release is low and constant; next, it increases progressively, and then it declines. In the LH-releasing patterns of pituitary glands of ovariectomized (OVX) rats, the initial phase is absent in vitro (Jutisz et al, 1975; Osland et al., 1975; de Koning et al., 1976a,b, 1978a) as well as in vivo (Schuiling and Gnodde, 1976, 1977).

Keywords

Luteinizing Hormone Pituitary Gland Protein Factor Luteinizing Hormone Surge Estradiol Benzoate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • Jurrien de Koning
    • 1
  • Hannie A. M. J. van Dieten
    • 1
  • G. Peter van Rees
    • 1
  1. 1.Sylvius Laboratories, Department of PharmacologyLeiden University Medical CenterLeidenThe Netherlands

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