Corticotropin Secretion

  • Mortyn T. Jones
  • Brian Gillham
Part of the Biochemical Endocrinology book series (BIOEND)


The secretion of corticotropin (ACTH) is episodic, with a frequency and duration that give rise to the familiar circadian rhythm in plasma ACTH and corticosteroid concentrations. ACTH is synthesized in the adenohy-pophysis and, in those species in which it persists into the postnatal period, the intermediate lobe. There seems little doubt, however, that the adenohypophysis is the major source of circulating ACTH.


Median Eminence ACTH Secretion ACTH Release Intermediate Lobe Portal Vessel 


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Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • Mortyn T. Jones
    • 1
  • Brian Gillham
    • 1
  1. 1.Sherrington School of Physiology and Department of BiochemistrySt. Thomas’s Hospital Medical SchoolLondon SE1England

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