Hormonal Regulation of Prolactin mRNA
The neuroendocrine regulation of pituitary hormone synthesis and secretion is a complex process in which polypeptide hormones, bioamines, and steroid hormones play a part. Various hormones have been documented to exert stimulatory or inhibitory effects on the biosynthesis and secretion of specific pituitary hormones. The molecular processes underlying these hormonally induced alterations are less well understood, but current data suggest that significant differences may exist in the actions of steroid and polypeptide hormones at the molecular level.
KeywordsGrowth Hormone Polypeptide Hormone Growth Hormone Cell Growth Hormone mRNA Prolactin Gene
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- Martin, T. F. J., and Tashjian, A. H., Jr., 1977, Cell culture studies of thyrotropin-releasing hormone action, in: Biochemical Actions of Hormones, Vol. IV (G. Litwack, ed.), pp. 270–312, Academic Press, New York.Google Scholar
- Monahan, J. J., Harris, S. E., and O’Malley, B. W., 1977, Analysis of cellular messenger RNA using complementary DNA probes, in: Receptors and Hormone Action, Vol. I (B. W. O’Malley and L. Birnbaumer, eds.), pp. 297–329, Academic Press, New York.Google Scholar
- Roberts, J. C., and Herbert, E., 1977, Characterization of a common precursor to corticotropin and β-lipotropin: Identification of β-lipotropin peptides and their arrangement relative to corticotropin in the precursor synthesized in a cell-free system, Proc. Natl. Acad. Sci. U.S.A. 74: 5300.PubMedCrossRefGoogle Scholar