Chemical Composition and Tumorigenicity of Tobacco Smoke

  • Dietrich Hoffmann
  • Ernest L. Wynder


Numerous biological studies have established the carcinogenicity of tobacco smoke. (1,2) Laboratory experiments identified three types of components which contribute to the overall carcinogenicity of the smoke. These are tumor initiators, tumor accelerators, and tumor promoters. (3)


Tobacco Smoke Tumor Initiator Anthranilic Acid Polynuclear Aromatic Hydrocarbon Mainstream Smoke 
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Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • Dietrich Hoffmann
    • 1
  • Ernest L. Wynder
    • 1
  1. 1.Division of Environmental CarcinogenesisAmerican Health FoundationNew YorkUSA

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