Abstract
Cigarette smoking has been associated with a number of diseases in man. In most cases this relationship has required a. long period of exposure and the incidence of disease is dependent upon the number of cigarettes consumed. Attempts to interrupt a sequence between smoking and disease have presented us with a. series of very complex problems, most of which have not yet been solved. First of all it is unlikely that any single constituent of cigarette smoke could account for all of the conditions which develop in a group of heavy cigarette smokers. Many separate assay procedures will be required to determine effects of cigarette design on the delivery of potentially hazardous agents in the smoke, and these procedures are not available today. I think it is fair to say that although no fully satisfying laboratory model of the various diseases is available, the models for carcinogenesis offer promise that something positive can be achieved in this area.
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Bock, F.G. (1972). Methods for Bioassays of Tobacco Smoke. In: Schmeltz, I. (eds) The Chemistry of Tobacco and Tobacco Smoke. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0462-4_8
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DOI: https://doi.org/10.1007/978-1-4757-0462-4_8
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