Use of Monoclonal Antibodies to Fibrinogen, Fibrin and Fibrin(Ogen) Degradation Products in Atherosclerosis

  • Alessandra Bini
  • Bohdan J. Kudryk
Part of the Nato ASI Series book series (NSSA, volume 219)


Fibrinogen is a soluble protein which is converted into an insoluble gel, fibrin, by thrombin. Fibrin formation is involved in the physiology of hemostasis and wound repair and in a number of pathological processes such as thrombosis, atherosclerosis, tumors, renal disease and inflammation.


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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Alessandra Bini
    • 1
    • 2
  • Bohdan J. Kudryk
    • 3
  1. 1.Consorzio Mario Negri SudIstituto di Ricerche Farmacologiche Mario NegriS. Maria ImbaroItaly
  2. 2.Department of PathologyCollege of Physicians and Surgeons of Columbia UniversityNew YorkUSA
  3. 3.Lindsley F. Kimball Research InstituteThe New York Blood CenterNew YorkUSA

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