Group VIA radiopharmaceuticals

  • Azuwuike Owunwanne
  • Mohan Patel
  • Samy Sadek


The elements of group VIA which have useful radionuclides for nuclear medicine studies are oxygen, selenium and tellurium. They have two electrons in their outermost shells and in general form covalent bonds. The useful radionuclides are oxygen-15, selenium-75 and tellurium-123m. The radiopharmaceuticals of oxygen-15 are described in Chapter 14 (positron emitters); selenium-75 taura-23-selena-25-homocholic acid (75Se-HCAT) is described in Chapter 15 (non-imaging). There are no available radiopharmaceuticals containing tellurium-123m. Selenium-75 /-selenomethionine was evaluated for pancreas imaging but because of high background radioactivity it is seldom used. Only selenium-75 selenomethyl norcholesterol is described in this chapter.


Sodium Borohydride 75Se Metal ICRP Publication Hydrogen Selenide Outermost Shell 
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  1. 1.
    Riley, A.L.M. (1978) The development of selenium-75 cholesterol analogues. J. Labelled Compounds Radiopharm., 16, 28–30.Google Scholar
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    Shapiro, B., Britton, K.E., Hawkins, L.A. and Edwards, C.R.W. (1981) Clinical experience with 75Se-selenomethylcholeserol adrenal imaging. Clin. Endocrinol, 15, 19–27.CrossRefGoogle Scholar
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    Hawkins, L.A., Britton, K.E. and Shapiro, B. (1980) Selenium 75 selenomethyl cholesterol: a new agent for quantitative functional scintigraphy of the adrenals: physical aspects. Br. J. Radiol, 53, 883–89.CrossRefGoogle Scholar
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    ICRP Publication 53 (1990) Radiation Dose to Patients from Radiopharmaceuticals, Pergamon Press, Oxford, pp. 151–52.Google Scholar

Copyright information

© Azuwuike Owunwanne, Mohan Patel and Samy Sadek 1995

Authors and Affiliations

  • Azuwuike Owunwanne
    • 1
  • Mohan Patel
    • 2
  • Samy Sadek
    • 3
  1. 1.Department of Nuclear Medicine, Faculty of MedicineKuwait UniversityKuwait
  2. 2.Kuwait Central Radiopharmacy Kuwait Cancer Control CenterMinistry of Public HealthKuwait
  3. 3.Department of Nuclear Medicine Faculty of MedicineKuwait UniversityKuwait

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