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Polymeric Antitumor Agents on a Molecular and Cellular Level

  • Klaus Dorn
  • Gerhard Hoerpel
  • Helmut Ringsdorf

Abstract

During the last 80 years polymer science developed from H. Staudinger’s controversial hypothesis of the existence of macromolecules to highly sophisticated applications such as polymers in medicine. Within the field of pharmacologically active polymers, the area of polymeric antitumor agents is a new and attractive field, where polymer scientists try to combine the advantages of macromolecular systems with the requirements of tumor therapy. That is to say, that polymer chemists have to enter neighboring fields, for example, the rapidly developing area of the life sciences. This interdisciplinary thinking may lead to new concepts, which could serve as guidelines in the thicket of facts arising from the innumerable attempts to contribute to the solution of the cancer problem. The present survey does not review the whole field of polymeric antitumor agents, but summarizes facts and speculations fitting into the hypothesis of antitumor agents on a molecular and cellular level.

Keywords

Cellular Level Drug Carrier Antitumor Agent Cell Uptake Polymeric Carrier 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Klaus Dorn
    • 1
  • Gerhard Hoerpel
    • 1
  • Helmut Ringsdorf
    • 1
  1. 1.Fachbereich Chemie, Institut für Organische ChemieJohannes Gutenberg-UniversitätMainzWest Germany

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