The Sulfur-Containing Amino Acid Pathway in Normal and Malignant Cell Growth

  • S. I. Baskin
  • K. Wakayama
  • T. Knight
  • J. H. Jepson
  • E. C. Besa
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 139)


Taurine is a highly acidic sulfur-containing amino acid which is not incorporated into protein, but appears to be an end product of methionine metabolism. Its high acidity (pKa 1.5 or less) and its oxidized nature suggest that by normal mechanisms it might be a readily excreted molecule and, thus, not to found in wide abundance. However, taurine is found to be widely distributed in animal tissues, especially during periods of cellular growth (15).


Precursor Amino Acid Sulfonyl Chloride Taurine Concentration Taurine Uptake L12l0 Cell 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • S. I. Baskin
    • 1
  • K. Wakayama
    • 2
  • T. Knight
    • 1
  • J. H. Jepson
    • 3
  • E. C. Besa
    • 1
  1. 1.Departments of Pharmacology and MedicineThe Medical College of PennsylvaniaPhiladelphiaUSA
  2. 2.Showa University School of MedicineYokohamaJapan
  3. 3.City of Hope Medical CenterDuarteUSA

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