Control of Cardiac Output in Sustained Essential Hypertenson: A Biomathematic Approach

  • M. E. Safar
  • NPh Chau
Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 62)


The study of hypertension in animals has considerably improved our understanding of hypertension in man. The advances made mainly concern malignant hypertension and secondary hypertension, such as Conn’s syndrome and reno-vascular disease; little progress has yet been made in sustained essential hypertension. This could be explained in two ways. Firstly, the basic mechanisms of experimental and essential hypertension are quite different. Secondly, the methods for exploring human and experimental hypertension are not similar. The same phenomena are consequently difficult to recognize.


Cardiac Output Mean Arterial Pressure Essential Hypertension Total Peripheral Resistance Human Hypertension 
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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • M. E. Safar
    • 1
    • 2
  • NPh Chau
    • 1
    • 2
  1. 1.Hypertension Research Center and the Diagnosis CenterBroussais HospitalParisFrance
  2. 2.UER of Saint QuentinUniversity of PicardieSaint QuentinFrance

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