Temperature Distribution and Transport of Heat in the Canine Myocardium

  • G. Elzinga
  • G. H. M. ten Velden
  • N. Westerhof
Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 62)


Under aerobic conditions energy is liberated in the heart by conversion of substrates into water and carbon dioxide. It leaves this organ in the form of work and heat. The amount of work can be determined rather precisely and with relative ease from pressure and flow in aorta and pulmonary artery (McDonald, 1974). The amount of heat produced cannot be measured so easily. This report deals with the measurement of total heat produced by the heart in the intact animal. Attempts to measure local heat production in the left ventricular wall will be discussed as well.


Heat Loss Myocardial Blood Flow Heat Production Left Ventricular Wall Metabolic Heat Production 


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  1. BACHE, R.J., COBB, F.R., and GREENFIELD, J.C. Jr. (1974): Myocardial blood flow distributed during ischemia-induced coronary vasodilation in the unanesthetized dog. J. Clin. Invest. 54: 1462–1472.CrossRefGoogle Scholar
  2. BUCKBERG, G.D., LUCK, J.C., HOFFMAN, J.I.E., ARCHIE, J.P., and FIXLER, D.E. (1971): Some sources of error in measuring regional blood flow with radioactive microspheres. J. Appl. Physiol. 31: 5988–604.Google Scholar
  3. CARSLAW, H.S., and JAEGER, J.C. (1978): “Conduction of Heat in Solids”. Oxford University Press, Oxford; reprinted from the second edition (1959).Google Scholar
  4. COULSON, R.L., and RUSY, B.F. (1973): A system for assessing mechanical performance, heat production, and oxygen utilization of isolated perfused whole hearts. Cardiovasc. Res. 7: 859–869.CrossRefGoogle Scholar
  5. COULSON, R.L. (1976): Energetics of isovolumic contractions of the isolated rabbit heart. J. Physiol. 260: 45–53.Google Scholar
  6. ELZINGA, G., and WESTERHOF, N. (1980): Pump function of the feline left heart; change with heart rate and its bearing on the energy balance. Cardiovasc. Res. 14: 81–92.CrossRefGoogle Scholar
  7. FRIEDBERG, G., and HORN, K.H. (1939): Acute myocardial infarction not due to coronary occlusion. JAMA 112: 1675–1679.CrossRefGoogle Scholar
  8. GIBBS, C.L. (1978): Cardiac energetics. Physiol. Rev. 58: 174–254.Google Scholar
  9. HORN, H., FIELD, L.E., DACK, S., and MASTER, A.M. (1950): Acute coronary insufficiency: pathological and physiological aspects. Analysis of twenty-five cases of subendocardial necrosis. Am. Heart J. 40: 63–80.CrossRefGoogle Scholar
  10. KJEKSHUS, J.K., and MJOS, O.D. (1971): Local metabolic rate and left ventricular oxygen consumption in the intact dog heart. Scand. J. Clin. Lab. Invest. 28: 389–393.CrossRefGoogle Scholar
  11. KUBLER, W., and SPIECKERMANN, P.G. (1970): Regulation of glycolysis in the ischemic and the anoxic myocardium. J. Mol. Cell. Cardiol. 1: 351–377.CrossRefGoogle Scholar
  12. MCDONALD, U.A. (1974): “Blood Flow in Arteries”. Second Edition. Edward Arnold, London.Google Scholar
  13. MCDONALD, R.H. Jr. (1971): Myocardial heat production: its relationship to tension development. Am. J. Physiol. 220: 894–900Google Scholar
  14. MENDLOWITZ, M. (1948): The specific heat of human blood. Science 107: 97–98.CrossRefGoogle Scholar
  15. NEILL, W.A., LEVINE, H.J., WAGMAN, R.J., MESSER, J.V., KRASNOW, N., and GORLIN, R. (1961): Left ventricular heat production measured by coronary flow and temperature gradient. J. Appl. Physiol. 16: 883–890.Google Scholar
  16. THEISOHN, M., FRIEDRICH, M., JUSTUS, P., GUTTLER, K., and KLAUS, W. (1977): Heat production and oxygen consumption of the isolated rabbit heart: their relation to mechanical function. Basic Res. Cardiol. 72: 19–33.CrossRefGoogle Scholar
  17. TEN VELDEN, G.H.M. (1982): Heat production of the canine left ventricle. PhD thesis. Free University, Amsterdam.Google Scholar
  18. TEN VELDEN, G.M.H., ELZINGA, G., and WESTERHOF, N. (1982): Left ventricular energetics — Heat loss and temperature distribution of canine myocardium. Circ. Res. 50: 63–73.Google Scholar
  19. SYMAN, J. Jr (1948): Heme proteins. Advances in Protein Chem. 4: 443–471.Google Scholar

Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • G. Elzinga
    • 1
  • G. H. M. ten Velden
    • 1
  • N. Westerhof
    • 1
  1. 1.Physiological LaboratoryFree UniversityAmsterdamThe Netherlands

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