AMP Deaminase from Necrotic Rat Heart
Adenylate deaminase isolated from the heart was shown to be regulated in a special way by phosphatidylcholine containing liposomes /Purzycka-Preis et al. 1978/. While the liposomes had no effect on the enzyme kinetics in the absence of ATP, the ATP-activated adenylate deaminase displayed a V-type activation under the influence of the liposomes. This effect of liposomes was observed with the enzyme isolated both from the pig /Purzycka et al. 1978/ and rat heart /Żydowo et al. 1980/, from several other rat tissues /Prus et al. 1980/ not however from skeletal muscle.
KeywordsAdenosine Adenine Purine Phosphatidylcholine Phosphocellulose
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