AMP Deaminase from Necrotic Rat Heart

  • Mariuz M. Żydowo
  • Olga Walentynowicz
  • Teresa Wrzołkowa
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 165)

Abstract

Adenylate deaminase isolated from the heart was shown to be regulated in a special way by phosphatidylcholine containing liposomes /Purzycka-Preis et al. 1978/. While the liposomes had no effect on the enzyme kinetics in the absence of ATP, the ATP-activated adenylate deaminase displayed a V-type activation under the influence of the liposomes. This effect of liposomes was observed with the enzyme isolated both from the pig /Purzycka et al. 1978/ and rat heart /Żydowo et al. 1980/, from several other rat tissues /Prus et al. 1980/ not however from skeletal muscle.

Keywords

Adenosine Adenine Purine Phosphatidylcholine Phosphocellulose 

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References

  1. Ogasawara, N., Goto, H., Yamada, Y., and Watanabe, T., 1978 Distribution of AMP-Deaminase Isozymes in Rat Tissues. Eur. J. Biochem. 87, 297–304CrossRefGoogle Scholar
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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • Mariuz M. Żydowo
    • 1
  • Olga Walentynowicz
    • 1
  • Teresa Wrzołkowa
    • 1
  1. 1.Department of Biochemistry and Laboratory of Electron MicroscopyAcademic Medical SchoolDębinki 1, GdańskPoland

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