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Influence of Cytostatics on ATP-Levels of Leukemic Cells

  • Rudolf Kuzmits
  • Paul Aiginger
  • Michael Frass
  • Gerhard Schopf
  • Helmut Rumpold
  • Hans P. Schwarz
  • Mathias M. Müller
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 165)

Abstract

The use of firefly bioluminescence offers a rapid and specific method to determine the ATP-concentrations in cells (1). Intracellular levels of ATP correlate to the cell viability (2). ATP-measurement has been applied to test the viability of blood cells (3); in tissue and cell culturing the number of viable cells, their physiological activity and cell death can be determined using the biolu-minescence-ATP-assay (4,5).

Keywords

Leukemic Cell Chronic Lymphocytic Leukemia Chronic Myeloid Leukemia Acute Leukemia Acute Leukemia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • Rudolf Kuzmits
    • 1
  • Paul Aiginger
    • 1
  • Michael Frass
    • 1
  • Gerhard Schopf
    • 1
    • 2
  • Helmut Rumpold
    • 1
    • 3
  • Hans P. Schwarz
    • 1
  • Mathias M. Müller
    • 1
    • 3
  1. 1.2nd Dept. of MedicineUniversity of ViennaAustria
  2. 2.Dept. of Medical ChemistryUniversity of ViennaAustria
  3. 3.2nd Dept. of SurgeryUniversity of ViennaAustria

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