Exploiting Biochemical Differences in Leukemia
Two enzymes, terminal deoxynucleotidyl transferase (TdT) and adenosine deaminase (ADA), play unique roles in DNA metabolism in the human immunological system. We have defined the relationship of these two enzymes to the disease course of chronic myelogenous leukemia and have established their utility as biological markers of disease activity.
KeywordsChronic Lymphocytic Leukemia Chronic Myelogenous Leukemia Adenosine Deaminase Terminal Deoxynucleotidyl Transferase Mycosis Fungoides
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