Biochemical, Physiological and Pathological Properties of Endogenous Digitalis-Like Compounds
Sodium and water homeostasis are regulated by intrarenal physical and hormonal factors and by extrarenal hormones. The latter include factors retaining Na+ and water, and factors eliminating Na+ while the sodium balance is positive. There is a relationship between arterial blood pressure, Na+ homeostasis and body fluid volumes (1), and an increase in blood pressure may result from the incapacity of the kidney to eliminate a Na+ and water loading (2). This renal defect in the excretion of Na+ leads to an extracellular volume expansion which in turn, increases the activity or the concentration of a natriuretic hormone through hypothalamic stimulation (2).
KeywordsEssential Hypertension Plasma Extract Active Acromegaly Anephric Patient Body Fluid Volume
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