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Cerebral Na Sensors and Na Appetite of Sheep

  • R. S. Weisinger
  • D. A. Denton
  • M. J. McKinley
  • J. B. Simpson
  • E. Tarjan
Part of the NATO ASI Series book series (NSSA, volume 105)

Abstract

Previous research4 has shown that the Na intake of sheep can be altered by lateral ventricular (IVT) infusions which alter the cerebrospinal fluid (CSF) Na concentration. For example, infusion of 0.7 M mannitol-CSF decreased CSF [Na] by 15–20 mM and increased the Na intake of both Na-deplete and Na-replete sheep. IVT infusion of 0.5 M NaCl-CSF increased the CSF [Na] by 15–20 mM and decreased Na intake of Na-deplete sheep.

Keywords

Access Period Increase Water Intake Salt Appetite Contralateral Carotid Artery Lateral Brain Ventricle 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    M. J. McKinley, P. Considine, D. A. Denton, L. G. Leksell, E. Tarjan and R. S. Weisinger, Cerebral sodium sensors, thirst and sodium balance in sheep, Adv. Physiol. Sci. 11: 637 (1981).Google Scholar
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    A. Muller, D. A. Denton, M. J. McKinley, E. Tarjan and R. S. Weisinger, Lowered cerebrospinal fluid sodium antagonizes effect of raised blood sodium on salt appetite, Am. J. Physiol. 244: R810 (1983).PubMedGoogle Scholar
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    R. S. Weisinger, P. Considine, D. A. Denton, L. G. Leksell, M. J. McKinley, D. Mouw, A. Muller and E. Tarjan, Role of sodium concentration of the cerebrospinal fluid in the salt appetite of sheep, Am. J. Physiol. 242: R51 (1982).PubMedGoogle Scholar
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    R. S. Weisinger, D. A. Denton, M. J. McKinley, A. Muller and E. Tarjan, Cerebrospinal fluid sodium concentration and sodium appetite, Appetite, 4: 239 (1983).Google Scholar

Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • R. S. Weisinger
    • 1
  • D. A. Denton
    • 1
  • M. J. McKinley
    • 1
  • J. B. Simpson
    • 1
  • E. Tarjan
    • 1
  1. 1.Howard Florey Institute of Experimental Physiology and MedicineUniversity of MelbourneParkvilleAustralia

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